F08H9.4 SHSP domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: F08H9.4
Official Full Name: SHSP domain-containing protein
Primary source: WormBase:WBGene00008592
Locus tag: CELE_F08H9.4
See related: AllianceGenome:WB:WBGene00008592
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable unfolded protein binding activity. Involved in response to topologically incorrect protein. Predicted to be active in cytoplasm and nucleus. Is expressed in excretory canal; head neurons; and ventral cord neurons. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See F08H9.4 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 2

Sequence:: Chromosome: V; NC_003283.11 (14463520..14464428, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F08H9.4 (e-PCR)
- UniSTS:316564

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables unfolded protein binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in protein refolding	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to heat	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to topologically incorrect protein	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: SHSP domain-containing protein

NP_001294695.1

Confirmed by transcript evidence

NP_506586.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

14463520..14464428 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_074185.5 → NP_506586.1 SHSP domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_506586.1

Status: REVIEWED

UniProtKB/TrEMBL

Q19228

Conserved Domains (1) summary

cd06526
Location:47 → 125

metazoan_ACD; Alpha-crystallin domain (ACD) of metazoan alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are ...
NM_001307766.1 → NP_001294695.1 SHSP domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001294695.1

Status: REVIEWED

UniProtKB/TrEMBL

N1NV13

Conserved Domains (1) summary

cd06526
Location:2 → 80

metazoan_ACD; Alpha-crystallin domain (ACD) of metazoan alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are ...