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    F32D8.12 D-lactate dehydrogenase (cytochrome) [ Caenorhabditis elegans ]

    Gene ID: 179506, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F32D8.12
    Official Full Name
    D-lactate dehydrogenase (cytochrome)
    Primary source
    WormBase:WBGene00009334
    Locus tag
    CELE_F32D8.12
    See related
    AllianceGenome:WB:WBGene00009334
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable D-lactate dehydrogenase (cytochrome) activity; D-lactate dehydrogenase activity; and flavin adenine dinucleotide binding activity. Predicted to be involved in lactate catabolic process. Predicted to be active in mitochondrion. Orthologous to human LDHD (lactate dehydrogenase D). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F32D8.12 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (10888717..10890996, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ATPase_AAA_core domain-containing protein Neighboring gene TIL domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene PIH1 N-terminal domain-containing protein Neighboring gene Protein YIPF

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    2. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables D-lactate dehydrogenase (cytochrome) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables D-lactate dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables flavin adenine dinucleotide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in lactate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    D-lactate dehydrogenase (cytochrome)
    NP_001023873.1
    • Confirmed by transcript evidence
    NP_001379315.1
    • Confirmed by transcript evidence
    NP_001379416.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      10888717..10890996 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392598.1 → NP_001379315.1  D-lactate dehydrogenase (cytochrome) [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8I4K2
      Conserved Domains (1) summary
      PLN02805
      Location:43 → 472
      PLN02805; D-lactate dehydrogenase [cytochrome]

    2. NM_001028702.7 → NP_001023873.1  D-lactate dehydrogenase (cytochrome) [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023873.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JLJ0
      Conserved Domains (1) summary
      PLN02805
      Location:43 → 458
      PLN02805; D-lactate dehydrogenase [cytochrome]

    3. NM_001392599.1 → NP_001379416.1  D-lactate dehydrogenase (cytochrome) [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JLI9
      Conserved Domains (1) summary
      PLN02805
      Location:1 → 381
      PLN02805; D-lactate dehydrogenase [cytochrome]
    Nucleotide Protein
    Heading Accession and Version

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