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    clik-1 Calponin-like protein OV9M [ Caenorhabditis elegans ]

    Gene ID: 179069, updated on 9-Dec-2024

    Summary

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    Official Symbol
    clik-1
    Official Full Name
    Calponin-like protein OV9M
    Primary source
    WormBase:WBGene00020808
    Locus tag
    CELE_T25F10.6
    See related
    AllianceGenome:WB:WBGene00020808
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization. Predicted to be active in actin cytoskeleton. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See clik-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (6765768..6768732, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Protein dbl-1 Neighboring gene Neur_chan_LBD domain-containing protein Neighboring gene Tetratricopeptide repeat protein 8 Neighboring gene Uncharacterized protein Neighboring gene Serpentine Receptor, class T Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Segregated localization of two calponin-related proteins within sarcomeric thin filaments in Caenorhabditis elegans striated muscle. Ono S. Cytoskeleton (Hoboken), 2024 Feb-Mar. PMID 37792405, Free PMC Article
    2. Two Caenorhabditis elegans calponin-related proteins have overlapping functions that maintain cytoskeletal integrity and are essential for reproduction. Ono S, et al. J Biol Chem, 2020 Aug 21. PMID 32554465, Free PMC Article
    3. An Efficient Genome Editing Strategy To Generate Putative Null Mutants in Caenorhabditis elegans Using CRISPR/Cas9. Wang H, et al. G3 (Bethesda), 2018 Nov 6. PMID 30224336, Free PMC Article
    4. The Caenorhabditis elegans muscle-affecting gene unc-87 encodes a novel thin filament-associated protein. Goetinck S, et al. J Cell Biol, 1994 Oct. PMID 7929573, Free PMC Article
    5. Identification of CED-3 substrates by a yeast-based screening method. Kim SY, et al. Mol Biotechnol, 2004 May. PMID 15122042

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Two Caenorhabditis elegans calponin-related proteins have overlapping functions that maintain cytoskeletal integrity and are essential for reproduction.
      Title: Two Caenorhabditis elegans calponin-related proteins have overlapping functions that maintain cytoskeletal integrity and are essential for reproduction.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Calponin-like protein OV9M
    NP_001024158.1
    • Confirmed by transcript evidence
    NP_001368068.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      6765768..6768732 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001028987.4 → NP_001024158.1  Calponin-like protein OV9M [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024158.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23050
      Conserved Domains (1) summary
      pfam00402
      Location:241 → 264
      Calponin; Calponin family repeat

    2. NM_001380677.2 → NP_001368068.1  Calponin-like protein OV9M [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0M6
      Conserved Domains (1) summary
      pfam00402
      Location:103 → 127
      Calponin; Calponin family repeat
    Nucleotide Protein
    Heading Accession and Version

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