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    ncs-3 EF-hand domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 186953, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ncs-3
    Official Full Name
    EF-hand domain-containing protein
    Primary source
    WormBase:WBGene00003565
    Locus tag
    CELE_K03E6.3
    See related
    AllianceGenome:WB:WBGene00003565
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in regulation of signal transduction. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See ncs-3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    6
    Sequence:
    Chromosome: X; NC_003284.9 (1054081..1056846)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Vesicle-trafficking protein SEC22b Neighboring gene Ovule protein Neighboring gene MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene Band 7 domain-containing protein;Protein unc-1 Neighboring gene B9 domain-containing protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The sequence and associated null phenotype of a C. elegans neurocalcin-like gene. Rajaram S, et al. Genesis, 2000 Apr. PMID 10748460
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    EF-hand domain-containing protein
    NP_508201.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      1054081..1056846
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075800.6 → NP_508201.2  EF-hand domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508201.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95ZR9
      Conserved Domains (2) summary
      COG5126
      Location:19 → 187
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
      cd00051
      Location:77 → 135
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    Nucleotide Protein
    Heading Accession and Version

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