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    decr-1.2 putative 2,4-dienoyl-CoA reductase decr-1.2 [(3E)-enoyl-CoA-producing] [ Caenorhabditis elegans ]

    Gene ID: 189090, updated on 9-Dec-2024

    Summary

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    Official Symbol
    decr-1.2
    Official Full Name
    putative 2,4-dienoyl-CoA reductase decr-1.2 [(3E)-enoyl-CoA-producing]
    Primary source
    WormBase:WBGene00012177
    Locus tag
    CELE_W01C9.4
    See related
    AllianceGenome:WB:WBGene00012177
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable 2,4-dienoyl-CoA reductase (NADPH) activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be active in mitochondrion. Orthologous to human DECR1 (2,4-dienoyl-CoA reductase 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See decr-1.2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (8545615..8546888)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene ncRNA Neighboring gene Globin domain-containing protein Neighboring gene Eukaryotic translation initiation factor 5A-2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables 2,4-dienoyl-CoA reductase (NADPH) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    putative 2,4-dienoyl-CoA reductase decr-1.2 [(3E)-enoyl-CoA-producing]
    NP_495805.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8545615..8546888
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063404.3 → NP_495805.1  putative 2,4-dienoyl-CoA reductase decr-1.2 [(3E)-enoyl-CoA-producing] [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495805.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q23116
      Conserved Domains (2) summary
      PRK07677
      Location:25 → 272
      PRK07677; short chain dehydrogenase; Provisional
      cd05369
      Location:23 → 274
      TER_DECR_SDR_a; Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q23116.1

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