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    ZK512.4 Signal recognition particle 9 kDa protein [ Caenorhabditis elegans ]

    Gene ID: 176293, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ZK512.4
    Official Full Name
    Signal recognition particle 9 kDa protein
    Primary source
    WormBase:WBGene00013984
    Locus tag
    CELE_ZK512.4
    See related
    AllianceGenome:WB:WBGene00013984
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable 7S RNA binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in cytoplasm. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Is expressed widely. Orthologous to human SRP9 (signal recognition particle 9). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ZK512.4 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003281.10 (9145340..9145959)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4 Neighboring gene Uncharacterized protein Neighboring gene ATP-dependent RNA helicase;putative ATP-dependent RNA helicase DDX55 homolog Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene RING finger protein nhl-1;RING-type domain-containing protein Neighboring gene Protein irld-34

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables 7S RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in SRP-dependent cotranslational protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in SRP-dependent cotranslational protein targeting to membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of translational elongation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of signal recognition particle IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of signal recognition particle, endoplasmic reticulum targeting IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of signal recognition particle, endoplasmic reticulum targeting IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Signal recognition particle 9 kDa protein
    NP_499026.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      9145340..9145959
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066625.4 → NP_499026.1  Signal recognition particle 9 kDa protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499026.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34642
      Conserved Domains (1) summary
      pfam05486
      Location:4 → 73
      SRP9-21; Signal recognition particle 9 kDa protein (SRP9)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34642.1

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