acl-1 Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: acl-1
Official Full Name: Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1
Primary source: WormBase:WBGene00010339
Locus tag: CELE_F59F4.4
See related: AllianceGenome:WB:WBGene00010339
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable 1-acylglycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in phosphatidic acid biosynthetic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in gonad. Orthologous to human AGPAT1 (1-acylglycerol-3-phosphate O-acyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See acl-1 in Genome Data Viewer

Location:: chromosome: X

Exon count:: 5

Sequence:: Chromosome: X; NC_003284.9 (15849885..15852001)

Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F59F4.4 (e-PCR)
- UniSTS:319453

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables 1-acylglycerol-3-phosphate O-acyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables 1-acylglycerol-3-phosphate O-acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in CDP-diacylglycerol biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in phosphatidic acid biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in phospholipid biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1

NP_510606.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003284.9 Reference assembly

Range

15849885..15852001

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_078205.9 → NP_510606.1 Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_510606.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q93783, Q93841

Conserved Domains (2) summary

cd07989
Location:65 → 243

LPLAT_AGPAT-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like

COG0204
Location:26 → 199

PlsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]