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    sgrR DNA-binding transcriptional dual regulator SgrR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944788, updated on 3-Dec-2024

    Summary

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    Official Symbol
    sgrR
    Official Full Name
    DNA-binding transcriptional dual regulator SgrR
    Primary source
    ECOCYC:EG12094
    Locus tag
    b0069
    See related
    ASAP:ABE-0000251
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0070; yabN
    Summary
    "SugaR transport-related Regulator" SgrR is negatively autoregulated and coordinately activates transcription of the divergent operon. [More information is available at EcoCyc: EG12094].
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    Genomic context

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    Sequence:
    NC_000913.3 (75644..77299, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene thiamine ABC transporter membrane subunit Neighboring gene thiamine ABC transporter periplasmic binding protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene PtsG glucose transporter inhibitor Neighboring gene sugar exporter SetA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Physiological consequences of small RNA-mediated regulation of glucose-phosphate stress. Vanderpool CK. Curr Opin Microbiol, 2007 Apr. PMID 17383224
    2. Systematic sequencing of the Escherichia coli genome: analysis of the 0-2.4 min region. Yura T, et al. Nucleic Acids Res, 1992 Jul 11. PMID 1630901, Free PMC Article
    3. The novel transcription factor SgrR coordinates the response to glucose-phosphate stress. Vanderpool CK, et al. J Bacteriol, 2007 Mar. PMID 17209026, Free PMC Article
    4. Involvement of a novel transcriptional activator and small RNA in post-transcriptional regulation of the glucose phosphoenolpyruvate phosphotransferase system. Vanderpool CK, et al. Mol Microbiol, 2004 Nov. PMID 15522088
    5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SgrR negatively autoregulates its own transcription in the presence and absence of glucose-phosphate stress.
      Title: The novel transcription factor SgrR coordinates the response to glucose-phosphate stress.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptide transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription cis-regulatory region binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in peptide transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA-binding transcriptional dual regulator SgrR

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      75644..77299 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414611.1 DNA-binding transcriptional dual regulator SgrR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414611.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0AAE9TL84
      Conserved Domains (1) summary
      PRK13626
      Location:1 → 551
      PRK13626; HTH-type transcriptional regulator SgrR
    Nucleotide Protein
    Heading Accession and Version

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    Other Literature Sources
    Molecular Biology Databases
    Research Materials