spcs1 signal peptidase complex subunit 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: spcs1provided by ZNC
Official Full Name: signal peptidase complex subunit 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-050809-130
See related: Ensembl:ENSDARG00000059298 AllianceGenome:ZFIN:ZDB-GENE-050809-130
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fa97f07; wu:fa97f07; zgc:110014
Summary: Predicted to be involved in protein targeting to ER and signal peptide processing. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be part of signal peptidase complex. Orthologous to human SPCS1 (signal peptidase complex subunit 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (3989406..3993503)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (3970019..3974116)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

z99207 (e-PCR), detects polymorphism
- UniSTS:238916

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in protein targeting to ER	IBA Inferred from Biological aspect of Ancestor more info
involved_in signal peptide processing	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within signal peptide processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of signal peptidase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of signal peptidase complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: signal peptidase complex subunit 1

Names: signal peptidase complex subunit 1 homolog

NP_001028274.1

EC 3.4.-.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.