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    tsga10 testis specific, 10 [ Danio rerio (zebrafish) ]

    Gene ID: 768146, updated on 4-Jan-2025

    Summary

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    Official Symbol
    tsga10provided by ZNC
    Official Full Name
    testis specific, 10provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061013-482
    See related
    Ensembl:ENSDARG00000052512 AllianceGenome:ZFIN:ZDB-GENE-061013-482
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:152952
    Summary
    Predicted to be located in cytoplasm. Is expressed in several structures, including brain; eye; gonad; somite; and spinal cord neural tube. Human ortholog(s) of this gene implicated in spermatogenic failure 26. Orthologous to human TSGA10 (testis specific 10). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See tsga10 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (49651025..49674006)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (49006589..49029586)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene collagen, type XVII, alpha 1a Neighboring gene STE20-like kinase b Neighboring gene uncharacterized LOC137495820 Neighboring gene cracd like b Neighboring gene uncharacterized LOC137495292

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Identification and expression analysis of zebrafish testis-specific gene 10 (tsga10). Asghari-Givehchi S, et al. Int J Dev Biol, 2019. PMID 32149372
    2. Metastasis-associated miR-23a from nasopharyngeal carcinoma-derived exosomes mediates angiogenesis by repressing a novel target gene TSGA10. Bao L, et al. Oncogene, 2018 May. PMID 29520105, Free PMC Article
    3. Zebrafish Establish Female Germ Cell Identity by Advancing Cell Proliferation and Meiosis. Pan YJ, et al. Front Cell Dev Biol, 2022. PMID 35445010, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    testis-specific gene 10 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077289.2 → NP_001070757.2  testis-specific gene 10 protein

      See identical proteins and their annotated locations for NP_001070757.2

      Status: PROVISIONAL

      Source sequence(s)
      BX321880, CU570972
      UniProtKB/TrEMBL
      A0A8M3AKV2, B8A4S2
      Related
      ENSDARP00000155584.1, ENSDART00000191296.1
      Conserved Domains (1) summary
      pfam07246
      Location:168 → 359
      Phlebovirus_NSM; Phlebovirus nonstructural protein NS-M

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      49651025..49674006
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005160116.3 → XP_005160173.1  testis-specific gene 10 protein isoform X1

      UniProtKB/TrEMBL
      A0A8M2B704
      Conserved Domains (3) summary
      COG1196
      Location:174 → 521
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG4913
      Location:16 → 308
      COG4913; Uncharacterized protein, contains a C-terminal ATPase domain [Function unknown]
      pfam07888
      Location:421 → 657
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

    2. XM_009294088.3 → XP_009292363.1  testis-specific gene 10 protein isoform X2

      UniProtKB/TrEMBL
      A0A8M3AK31
      Conserved Domains (3) summary
      COG1196
      Location:174 → 521
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG4913
      Location:16 → 308
      COG4913; Uncharacterized protein, contains a C-terminal ATPase domain [Function unknown]
      pfam07888
      Location:421 → 657
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

    3. XM_009294092.3 → XP_009292367.1  testis-specific gene 10 protein isoform X3

      See identical proteins and their annotated locations for XP_009292367.1

      UniProtKB/TrEMBL
      A0A8M3AKV2, B8A4S2
      Related
      ENSDARP00000068869.5, ENSDART00000074380.7
      Conserved Domains (1) summary
      pfam07246
      Location:168 → 359
      Phlebovirus_NSM; Phlebovirus nonstructural protein NS-M

    4. XM_009294094.3 → XP_009292369.1  testis-specific gene 10 protein isoform X4

      UniProtKB/TrEMBL
      A0A8M3AVE5
      Conserved Domains (1) summary
      pfam07246
      Location:168 → 359
      Phlebovirus_NSM; Phlebovirus nonstructural protein NS-M
    Nucleotide Protein Strain
    Heading Accession and Version

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