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    cndp2 carnosine dipeptidase 2 [ Danio rerio (zebrafish) ]

    Gene ID: 327288, updated on 4-Jan-2025

    Summary

    Official Symbol
    cndp2provided by ZNC
    Official Full Name
    carnosine dipeptidase 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5499
    See related
    Ensembl:ENSDARG00000003931 AllianceGenome:ZFIN:ZDB-GENE-030131-5499
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    CN2; zgc:92569; wu:fd20d11; wu:fe17f09
    Summary
    Predicted to enable dipeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in cytosol. Is expressed in several structures, including intermediate cell mass of mesoderm; lens; neural crest; solid lens vesicle; and yolk syncytial layer. Orthologous to human CNDP2 (carnosine dipeptidase 2). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    NEW
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    Genomic context

    See cndp2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (20801066..20823101)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (21216741..21238778)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488436 Neighboring gene ADNP homeobox 2b Neighboring gene thioredoxin-like 4A Neighboring gene uncharacterized LOC137488506 Neighboring gene teashirt zinc finger homeobox 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables carboxypeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables dipeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables dipeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metallodipeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    cytosolic non-specific dipeptidase
    Names
    CNDP dipeptidase 2 (metallopeptidase M20 family)
    NP_999869.2
    XP_005170061.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214704.2NP_999869.2  cytosolic non-specific dipeptidase

      See identical proteins and their annotated locations for NP_999869.2

      Status: VALIDATED

      Source sequence(s)
      BQ263633, BX957344, DY546953, EH500533
      UniProtKB/TrEMBL
      A0A8M1PK12, A3KQX1
      Related
      ENSDARP00000033632.5, ENSDART00000038202.6
      Conserved Domains (1) summary
      cd05676
      Location:7473
      M20_dipept_like_CNDP; M20 cytosolic nonspecific dipeptidases including anserinase and serum carnosinase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      20801066..20823101
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005170004.5XP_005170061.1  cytosolic non-specific dipeptidase isoform X1

      See identical proteins and their annotated locations for XP_005170061.1

      UniProtKB/TrEMBL
      A0A8M1PK12, A3KQX1
      Related
      ENSDARP00000120032.2, ENSDART00000143457.4
      Conserved Domains (1) summary
      cd05676
      Location:7473
      M20_dipept_like_CNDP; M20 cytosolic nonspecific dipeptidases including anserinase and serum carnosinase