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    hyfA hydrogenase 4 component A [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946959, updated on 3-Dec-2024

    Summary

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    Official Symbol
    hyfA
    Official Full Name
    hydrogenase 4 component A
    Primary source
    ECOCYC:EG11150
    Locus tag
    b2481
    See related
    ASAP:ABE-0008179
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2477; yffE
    Summary
    This subunit contains four 4Fe-4S clusters and may be involved in electron transfer. [More information is available at EcoCyc: EG11150].
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    Genomic context

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    Sequence:
    NC_000913.3 (2601201..2601818)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 4-hydroxy-tetrahydrodipicolinate synthase Neighboring gene putative transcriptional regulator GcvR Neighboring gene thiol peroxidase Neighboring gene hydrogenase 4 component B Neighboring gene hydrogenase 4 component C

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A molecular analysis of the 53.3 minute region of the Escherichia coli linkage map. Andrews SC, et al. J Gen Microbiol, 1991 Feb. PMID 2016588
    2. Participation of hyf-encoded hydrogenase 4 in molecular hydrogen release coupled with proton-potassium exchange in Escherichia coli. Bagramyan K, et al. Membr Cell Biol, 2001. PMID 11817571
    3. Phosphorylation of ribosomal proteins in HeLa cells infected with vaccinia virus. Kaerlein M, et al. Nature, 1976 Jan 15. PMID 1246353
    4. Expression and regulation of a silent operon, hyf, coding for hydrogenase 4 isoenzyme in Escherichia coli. Self WT, et al. J Bacteriol, 2004 Jan. PMID 14702328, Free PMC Article
    5. Quantitative whole-genome analysis of DNA-protein interactions by in vivo methylase protection in E. coli. Tavazoie S, et al. Nat Biotechnol, 1998 Jun. PMID 9624689

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of [Ni-Fe] hydrogenase complex RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hydrogenase 4 component A

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2601201..2601818
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416976.4 hydrogenase 4 component A [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416976.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A7L7EHY9
      Conserved Domains (1) summary
      cd10554
      Location:4 → 170
      HycB_like; HycB, HydN and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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