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    Pdzk1ip1 PDZK1 interacting protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 67182, updated on 27-Dec-2024

    Summary

    Official Symbol
    Pdzk1ip1provided by MGI
    Official Full Name
    PDZK1 interacting protein 1provided by MGI
    Primary source
    MGI:MGI:1914432
    See related
    Ensembl:ENSMUSG00000028716 AllianceGenome:MGI:1914432
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Map17; 0610007F13Rik; 2700030M23Rik
    Summary
    Predicted to be located in apical plasma membrane. Is expressed in several structures, including central nervous system; dorsal aorta; metanephros; naris; and retina. Orthologous to human PDZK1IP1 (PDZK1 interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in kidney adult (RPKM 657.0), colon adult (RPKM 64.0) and 3 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Pdzk1ip1 in Genome Data Viewer
    Location:
    4 D1; 4 52.75 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (114945905..114951091)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (115088708..115093894)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 52674 Neighboring gene predicted gene, 33786 Neighboring gene T cell acute lymphocytic leukemia 1 Neighboring gene cytochrome P450, family 4, subfamily x, polypeptide 1 Neighboring gene cytochrome P450, family 4, subfamily x, polypeptide 1, opposite strand Neighboring gene cytochrome P450, family 4, subfamily a, polypeptide 28, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in apical plasma membrane  

    General protein information

    Preferred Names
    PDZK1-interacting protein 1
    Names
    17 kDa membrane-associated protein
    membrane-associated protein 17 (Map17)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164557.1NP_001158029.1  PDZK1-interacting protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001158029.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK007936, AL670035, DV058382, EH108199
      Consensus CDS
      CCDS51272.1
      UniProtKB/TrEMBL
      G3UW41
      Related
      ENSMUSP00000128118.2, ENSMUST00000171877.8
      Conserved Domains (1) summary
      pfam15807
      Location:84181
      MAP17; Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
    2. NM_001164558.1NP_001158030.1  PDZK1-interacting protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001158030.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks a segment of the 5' UTR and 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1. Both variants 2 and 3 encode the same isoform.
      Source sequence(s)
      AL645473, AL670035, DV057288, DV058382
      Consensus CDS
      CCDS18487.1
      UniProtKB/Swiss-Prot
      Q9CQH0
      UniProtKB/TrEMBL
      A8C1X3
      Related
      ENSMUSP00000136049.2, ENSMUST00000177647.8
      Conserved Domains (1) summary
      pfam15807
      Location:6114
      MAP17; Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
    3. NM_026018.3NP_080294.1  PDZK1-interacting protein 1 isoform 2

      See identical proteins and their annotated locations for NP_080294.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks a segment of the 5' UTR and 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1. Both variants 2 and 3 encode the same isoform.
      Source sequence(s)
      AK008253, AL670035, DV058382
      Consensus CDS
      CCDS18487.1
      UniProtKB/Swiss-Prot
      Q9CQH0
      UniProtKB/TrEMBL
      A8C1X3
      Related
      ENSMUSP00000102158.3, ENSMUST00000106548.9
      Conserved Domains (1) summary
      pfam15807
      Location:6114
      MAP17; Membrane-associated protein 117 kDa, PDZK1-interacting protein 1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      114945905..114951091
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030253719.2XP_030109579.1  PDZK1-interacting protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q9CQH0
      UniProtKB/TrEMBL
      A8C1X3
      Conserved Domains (1) summary
      pfam15807
      Location:6114
      MAP17; Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
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