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    Slc12a9 solute carrier family 12 (potassium/chloride transporters), member 9 [ Mus musculus (house mouse) ]

    Gene ID: 83704, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slc12a9provided by MGI
    Official Full Name
    solute carrier family 12 (potassium/chloride transporters), member 9provided by MGI
    Primary source
    MGI:MGI:1933532
    See related
    Ensembl:ENSMUSG00000037344 AllianceGenome:MGI:1933532
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CIP1
    Summary
    Predicted to enable potassium:chloride symporter activity. Predicted to be involved in several processes, including chloride ion homeostasis; chloride transmembrane transport; and potassium ion homeostasis. Predicted to be located in membrane. Is expressed in genitourinary system; integumental system; nervous system; sensory organ; and skeleton. Orthologous to human SLC12A9 (solute carrier family 12 member 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 11.1), adrenal adult (RPKM 11.0) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Slc12a9 in Genome Data Viewer
    Location:
    5 G2; 5 76.35 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (137312820..137338331, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (137314558..137340070, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene 43013 Neighboring gene thyroid hormone receptor interactor 6 Neighboring gene STARR-positive B cell enhancer ABC_E9655 Neighboring gene STARR-seq mESC enhancer starr_14641 Neighboring gene predicted gene, 52791 Neighboring gene Eph receptor B4 Neighboring gene STARR-seq mESC enhancer starr_14643

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2) 

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in cell volume homeostasis  
    involved_in chloride ion homeostasis  
    involved_in chloride transmembrane transport  
    involved_in chloride transmembrane transport  
    involved_in inorganic cation transmembrane transport  
    involved_in metal ion transport  
    involved_in potassium ion homeostasis  
    Component Evidence Code Pubs
    located_in lysosomal membrane  
    located_in membrane PubMed 
    located_in plasma membrane  

    General protein information

    Preferred Names
    solute carrier family 12 member 9
    Names
    cation-chloride cotransporter-interacting protein 1
    potassium-chloride transporter 9

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359611.1NP_001346540.1  solute carrier family 12 member 9

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AC150682
      Consensus CDS
      CCDS19766.1
      UniProtKB/Swiss-Prot
      E9QNN4, Q99MR3
      Conserved Domains (1) summary
      TIGR00930
      Location:36905
      2a30; K-Cl cotransporter
    2. NM_031406.3NP_113583.2  solute carrier family 12 member 9

      See identical proteins and their annotated locations for NP_113583.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AC150682
      Consensus CDS
      CCDS19766.1
      UniProtKB/Swiss-Prot
      E9QNN4, Q99MR3
      Related
      ENSMUSP00000038106.8, ENSMUST00000039991.14
      Conserved Domains (1) summary
      TIGR00930
      Location:36905
      2a30; K-Cl cotransporter

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      137312820..137338331 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030254934.2XP_030110794.1  solute carrier family 12 member 9 isoform X1

      UniProtKB/Swiss-Prot
      E9QNN4, Q99MR3
      Conserved Domains (1) summary
      TIGR00930
      Location:36905
      2a30; K-Cl cotransporter
    2. XM_030254938.2XP_030110798.1  solute carrier family 12 member 9 isoform X1

      UniProtKB/Swiss-Prot
      E9QNN4, Q99MR3
      Conserved Domains (1) summary
      TIGR00930
      Location:36905
      2a30; K-Cl cotransporter
    3. XM_030254937.2XP_030110797.1  solute carrier family 12 member 9 isoform X1

      UniProtKB/Swiss-Prot
      E9QNN4, Q99MR3
      Conserved Domains (1) summary
      TIGR00930
      Location:36905
      2a30; K-Cl cotransporter
    4. XM_030254933.2XP_030110793.1  solute carrier family 12 member 9 isoform X1

      UniProtKB/Swiss-Prot
      E9QNN4, Q99MR3
      Conserved Domains (1) summary
      TIGR00930
      Location:36905
      2a30; K-Cl cotransporter
    5. XM_036165634.1XP_036021527.1  solute carrier family 12 member 9 isoform X1

      UniProtKB/Swiss-Prot
      E9QNN4, Q99MR3
      Conserved Domains (1) summary
      TIGR00930
      Location:36905
      2a30; K-Cl cotransporter
    6. XM_030254931.2XP_030110791.1  solute carrier family 12 member 9 isoform X1

      UniProtKB/Swiss-Prot
      E9QNN4, Q99MR3
      Conserved Domains (1) summary
      TIGR00930
      Location:36905
      2a30; K-Cl cotransporter
    7. XM_030254935.2XP_030110795.1  solute carrier family 12 member 9 isoform X1

      UniProtKB/Swiss-Prot
      E9QNN4, Q99MR3
      Conserved Domains (1) summary
      TIGR00930
      Location:36905
      2a30; K-Cl cotransporter
    8. XM_030254932.2XP_030110792.1  solute carrier family 12 member 9 isoform X1

      UniProtKB/Swiss-Prot
      E9QNN4, Q99MR3
      Conserved Domains (1) summary
      TIGR00930
      Location:36905
      2a30; K-Cl cotransporter
    9. XM_030254936.1XP_030110796.1  solute carrier family 12 member 9 isoform X1

      UniProtKB/Swiss-Prot
      E9QNN4, Q99MR3
      Conserved Domains (1) summary
      TIGR00930
      Location:36905
      2a30; K-Cl cotransporter

    RNA

    1. XR_001784760.3 RNA Sequence

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