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    Lypd2 Ly6/Plaur domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 68311, updated on 9-Dec-2024

    Summary

    Official Symbol
    Lypd2provided by MGI
    Official Full Name
    Ly6/Plaur domain containing 2provided by MGI
    Primary source
    MGI:MGI:1915561
    See related
    Ensembl:ENSMUSG00000022595 AllianceGenome:MGI:1915561
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    VLL; Lypdc2; 0610005K03Rik
    Summary
    Predicted to be located in plasma membrane and side of membrane. Is expressed in future spinal cord; hindbrain; midbrain; and telencephalon. Orthologous to human LYPD2 (LY6/PLAUR domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in lung adult (RPKM 49.0), kidney adult (RPKM 10.0) and 1 other tissue See more
    Orthologs
    NEW
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    Genomic context

    See Lypd2 in Genome Data Viewer
    Location:
    15 D3; 15 34.26 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (74604095..74606644, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (74732246..74734795, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:74553786-74554003 Neighboring gene thioesterase superfamily member 6 Neighboring gene secreted Ly6/Plaur domain containing 1 Neighboring gene predicted gene, 33124 Neighboring gene secreted Ly6/Plaur domain containing 2

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1)  1 citation

    General gene information

    Clone Names

    • MGC117783

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ly6/PLAUR domain-containing protein 2
    Names
    H8C4 protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026671.1NP_080947.1  ly6/PLAUR domain-containing protein 2 precursor

      See identical proteins and their annotated locations for NP_080947.1

      Status: PROVISIONAL

      Source sequence(s)
      BC099511
      Consensus CDS
      CCDS27529.1
      UniProtKB/Swiss-Prot
      A2RT83, Q9DD23
      Related
      ENSMUSP00000023260.4, ENSMUST00000023260.5
      Conserved Domains (1) summary
      cd00117
      Location:23102
      LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      74604095..74606644 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006521312.1XP_006521375.1  ly6/PLAUR domain-containing protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006521375.1

      UniProtKB/Swiss-Prot
      A2RT83, Q9DD23
      Conserved Domains (1) summary
      cd00117
      Location:23102
      LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...