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    VPS8 VPS8 subunit of CORVET complex [ Homo sapiens (human) ]

    Gene ID: 23355, updated on 10-Dec-2024

    Summary

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    Official Symbol
    VPS8provided by HGNC
    Official Full Name
    VPS8 subunit of CORVET complexprovided by HGNC
    Primary source
    HGNC:HGNC:29122
    See related
    Ensembl:ENSG00000156931 MIM:618366; AllianceGenome:HGNC:29122
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    KIAA0804
    Summary
    Predicted to enable metal ion binding activity. Involved in endosomal vesicle fusion. Located in early endosome. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis (RPKM 8.2), brain (RPKM 7.7) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See VPS8 in Genome Data Viewer
    Location:
    3q27.2
    Exon count:
    59
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (184812166..185052614)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (187627968..187868623)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (184529954..184770402)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374253 Neighboring gene Sharpr-MPRA regulatory region 13352 Neighboring gene long intergenic non-protein coding RNA 2069 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:184498897-184499397 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:184508256-184508756 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20914 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20915 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14970 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14971 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20916 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr3:184624367-184625028 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr3:184625029-184625689 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr3:184629832-184630395 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:184787208-184787708 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:184788784-184788991 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:184792904-184793404 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:184797955-184798456 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:184798457-184798956 Neighboring gene Sharpr-MPRA regulatory region 10617 Neighboring gene chromosome 3 open reading frame 70 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14972 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20917 Neighboring gene H3K27ac-H3K4me1 hESC enhancers GRCh37_chr3:184892998-184893522 and GRCh37_chr3:184893523-184894047 Neighboring gene EHHADH antisense RNA 1 Neighboring gene enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions. Jonker CTH, et al. Nat Commun, 2018 Feb 23. PMID 29476049, Free PMC Article
    2. CORVET, CHEVI and HOPS - multisubunit tethers of the endo-lysosomal system in health and disease. van der Beek J, et al. J Cell Sci, 2019 May 15. PMID 31092635
    3. VPS18 recruits VPS41 to the human HOPS complex via a RING-RING interaction. Hunter MR, et al. Biochem J, 2017 Oct 23. PMID 28931724, Free PMC Article
    4. Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity. van der Kant R, et al. J Biol Chem, 2015 Dec 18. PMID 26463206, Free PMC Article
    5. Mammalian CORVET is required for fusion and conversion of distinct early endosome subpopulations. Perini ED, et al. Traffic, 2014 Dec. PMID 25266290

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Vps3 and Vps8 are required for recycling of beta1 integrins.
      Title: Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions.
    2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
      Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus.
    EBI GWAS Catalog
    Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ32099

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endosomal vesicle fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endosomal vesicle fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in endosomal vesicle fusion NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in protein targeting to vacuole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of SNARE complex assembly NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of CORVET complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of CORVET complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of HOPS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in early endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in early endosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in late endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    vacuolar protein sorting-associated protein 8 homolog
    Names
    VPS8, CORVET complex subunit
    vacuolar protein sorting 8 homolog

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009921.3 → NP_001009921.1  vacuolar protein sorting-associated protein 8 homolog isoform a

      See identical proteins and their annotated locations for NP_001009921.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1, 3, 4, 5, and 6 all encode the same isoform (a).
      Source sequence(s)
      AB018347, AC117436, AK056661, BI914013, DA218768, DA340096
      Consensus CDS
      CCDS46971.1
      UniProtKB/Swiss-Prot
      A8K8Q8, B9EIQ1, C9JB61, O94896, Q63HP2, Q8N3P4, Q9BVP9, Q9H9B0
      UniProtKB/TrEMBL
      C9JJN9
      Related
      ENSP00000487164.1, ENST00000625842.3
      Conserved Domains (4) summary
      sd00039
      Location:202 → 239
      7WD40; WD40 repeat [structural motif]
      pfam12816
      Location:614 → 796
      Vps8; Golgi CORVET complex core vacuolar protein 8
      cd16687
      Location:1256 → 1310
      RING-H2_Vps8; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 8 (Vps8) and similar proteins
      cl25539
      Location:197 → 298
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_001349292.2 → NP_001336221.1  vacuolar protein sorting-associated protein 8 homolog isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3), as well as variants 1, 4, 5, and 6, encodes isoform a.
      Source sequence(s)
      AC025573, AC107294, AC117436
      Consensus CDS
      CCDS46971.1
      UniProtKB/Swiss-Prot
      A8K8Q8, B9EIQ1, C9JB61, O94896, Q63HP2, Q8N3P4, Q9BVP9, Q9H9B0
      UniProtKB/TrEMBL
      C9JJN9
      Conserved Domains (4) summary
      sd00039
      Location:202 → 239
      7WD40; WD40 repeat [structural motif]
      pfam12816
      Location:614 → 796
      Vps8; Golgi CORVET complex core vacuolar protein 8
      cd16687
      Location:1256 → 1310
      RING-H2_Vps8; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 8 (Vps8) and similar proteins
      cl25539
      Location:197 → 298
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. NM_001349293.2 → NP_001336222.1  vacuolar protein sorting-associated protein 8 homolog isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4), as well as variants 1, 3, 5, and 6, encodes isoform a.
      Source sequence(s)
      AC025573, AC107294, AC117436
      Consensus CDS
      CCDS46971.1
      UniProtKB/Swiss-Prot
      A8K8Q8, B9EIQ1, C9JB61, O94896, Q63HP2, Q8N3P4, Q9BVP9, Q9H9B0
      UniProtKB/TrEMBL
      C9JJN9
      Conserved Domains (4) summary
      sd00039
      Location:202 → 239
      7WD40; WD40 repeat [structural motif]
      pfam12816
      Location:614 → 796
      Vps8; Golgi CORVET complex core vacuolar protein 8
      cd16687
      Location:1256 → 1310
      RING-H2_Vps8; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 8 (Vps8) and similar proteins
      cl25539
      Location:197 → 298
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    4. NM_001349294.2 → NP_001336223.1  vacuolar protein sorting-associated protein 8 homolog isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5), as well as variants 1, 3, 4, and 6, encodes isoform a.
      Source sequence(s)
      AC025573, AC107294, AC117436
      Consensus CDS
      CCDS46971.1
      UniProtKB/Swiss-Prot
      A8K8Q8, B9EIQ1, C9JB61, O94896, Q63HP2, Q8N3P4, Q9BVP9, Q9H9B0
      UniProtKB/TrEMBL
      C9JJN9
      Conserved Domains (4) summary
      sd00039
      Location:202 → 239
      7WD40; WD40 repeat [structural motif]
      pfam12816
      Location:614 → 796
      Vps8; Golgi CORVET complex core vacuolar protein 8
      cd16687
      Location:1256 → 1310
      RING-H2_Vps8; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 8 (Vps8) and similar proteins
      cl25539
      Location:197 → 298
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    5. NM_001349295.1 → NP_001336224.1  vacuolar protein sorting-associated protein 8 homolog isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6), as well as variants 1, 3, 4, and 5, encodes isoform a.
      Source sequence(s)
      AC025573, AC107294, AC117436
      Consensus CDS
      CCDS46971.1
      UniProtKB/Swiss-Prot
      A8K8Q8, B9EIQ1, C9JB61, O94896, Q63HP2, Q8N3P4, Q9BVP9, Q9H9B0
      UniProtKB/TrEMBL
      C9JJN9
      Conserved Domains (4) summary
      sd00039
      Location:202 → 239
      7WD40; WD40 repeat [structural motif]
      pfam12816
      Location:614 → 796
      Vps8; Golgi CORVET complex core vacuolar protein 8
      cd16687
      Location:1256 → 1310
      RING-H2_Vps8; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 8 (Vps8) and similar proteins
      cl25539
      Location:197 → 298
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    6. NM_001349296.2 → NP_001336225.1  vacuolar protein sorting-associated protein 8 homolog isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) encodes isoform c.
      Source sequence(s)
      AC025573, AC107294, AC117436
      UniProtKB/TrEMBL
      C9JJN9
      Conserved Domains (4) summary
      sd00039
      Location:189 → 226
      7WD40; WD40 repeat [structural motif]
      pfam12816
      Location:601 → 783
      Vps8; Golgi CORVET complex core vacuolar protein 8
      cd16687
      Location:1243 → 1297
      RING-H2_Vps8; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 8 (Vps8) and similar proteins
      cl25539
      Location:91 → 294
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    7. NM_001349297.2 → NP_001336226.1  vacuolar protein sorting-associated protein 8 homolog isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) encodes isoform d.
      Source sequence(s)
      AC025573, AC107294, AC117436
      Conserved Domains (2) summary
      pfam12816
      Location:41 → 223
      Vps8; Golgi CORVET complex core vacuolar protein 8
      cd16687
      Location:683 → 737
      RING-H2_Vps8; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 8 (Vps8) and similar proteins

    8. NM_001349298.2 → NP_001336227.1  vacuolar protein sorting-associated protein 8 homolog isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) encodes isoform e.
      Source sequence(s)
      AC025573, AC107294, AC117436
      Conserved Domains (2) summary
      pfam12816
      Location:14 → 196
      Vps8; Golgi CORVET complex core vacuolar protein 8
      cd16687
      Location:656 → 710
      RING-H2_Vps8; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 8 (Vps8) and similar proteins

    9. NM_015303.4 → NP_056118.2  vacuolar protein sorting-associated protein 8 homolog isoform b

      See identical proteins and their annotated locations for NP_056118.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
      Source sequence(s)
      AC025573, AC107294, AC117436
      Consensus CDS
      CCDS46972.1
      UniProtKB/TrEMBL
      C9JJN9
      Related
      ENSP00000404704.2, ENST00000436792.6
      Conserved Domains (4) summary
      sd00039
      Location:200 → 237
      7WD40; WD40 repeat [structural motif]
      pfam12816
      Location:612 → 794
      Vps8; Golgi CORVET complex core vacuolar protein 8
      cd16687
      Location:1254 → 1308
      RING-H2_Vps8; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 8 (Vps8) and similar proteins
      cl25539
      Location:195 → 296
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RNA

    1. NR_146113.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC025573, AC107294, AC117436

    2. NR_146114.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC107294
      Related
      ENST00000485024.1

    3. NR_146115.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC107294

    4. NR_146116.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC107294

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

      Range
      184812166..185052614
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047447824.1 → XP_047303780.1  vacuolar protein sorting-associated protein 8 homolog isoform X2

      UniProtKB/TrEMBL
      C9JJN9

    2. XM_024453426.2 → XP_024309194.1  vacuolar protein sorting-associated protein 8 homolog isoform X1

      UniProtKB/Swiss-Prot
      A8K8Q8, B9EIQ1, C9JB61, O94896, Q63HP2, Q8N3P4, Q9BVP9, Q9H9B0
      UniProtKB/TrEMBL
      C9JJN9
      Conserved Domains (4) summary
      sd00039
      Location:202 → 239
      7WD40; WD40 repeat [structural motif]
      pfam12816
      Location:614 → 796
      Vps8; Golgi CORVET complex core vacuolar protein 8
      cd16687
      Location:1256 → 1310
      RING-H2_Vps8; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 8 (Vps8) and similar proteins
      cl25539
      Location:197 → 298
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. XM_047447823.1 → XP_047303779.1  vacuolar protein sorting-associated protein 8 homolog isoform X2

      UniProtKB/TrEMBL
      C9JJN9

    4. XM_024453428.2 → XP_024309196.1  vacuolar protein sorting-associated protein 8 homolog isoform X2

      UniProtKB/TrEMBL
      C9JJN9
      Conserved Domains (4) summary
      sd00039
      Location:200 → 237
      7WD40; WD40 repeat [structural motif]
      pfam12816
      Location:612 → 794
      Vps8; Golgi CORVET complex core vacuolar protein 8
      cd16687
      Location:1254 → 1308
      RING-H2_Vps8; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 8 (Vps8) and similar proteins
      cl25539
      Location:195 → 296
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    5. XM_005247253.6 → XP_005247310.1  vacuolar protein sorting-associated protein 8 homolog isoform X4

      UniProtKB/TrEMBL
      B3KPR6
      Conserved Domains (2) summary
      sd00039
      Location:202 → 239
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:197 → 298
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    6. XM_047447827.1 → XP_047303783.1  vacuolar protein sorting-associated protein 8 homolog isoform X5

      UniProtKB/TrEMBL
      B3KPR6

    7. XM_017006041.3 → XP_016861530.1  vacuolar protein sorting-associated protein 8 homolog isoform X9

    8. XM_047447828.1 → XP_047303784.1  vacuolar protein sorting-associated protein 8 homolog isoform X10

    9. XM_047447821.1 → XP_047303777.1  vacuolar protein sorting-associated protein 8 homolog isoform X1

      UniProtKB/Swiss-Prot
      A8K8Q8, B9EIQ1, C9JB61, O94896, Q63HP2, Q8N3P4, Q9BVP9, Q9H9B0
      UniProtKB/TrEMBL
      C9JJN9

    10. XM_047447825.1 → XP_047303781.1  vacuolar protein sorting-associated protein 8 homolog isoform X2

      UniProtKB/TrEMBL
      C9JJN9

    11. XM_047447822.1 → XP_047303778.1  vacuolar protein sorting-associated protein 8 homolog isoform X1

      UniProtKB/Swiss-Prot
      A8K8Q8, B9EIQ1, C9JB61, O94896, Q63HP2, Q8N3P4, Q9BVP9, Q9H9B0
      UniProtKB/TrEMBL
      C9JJN9

    12. XM_047447826.1 → XP_047303782.1  vacuolar protein sorting-associated protein 8 homolog isoform X3

      UniProtKB/TrEMBL
      C9JJN9

    13. XM_011512599.3 → XP_011510901.1  vacuolar protein sorting-associated protein 8 homolog isoform X6

      Conserved Domains (2) summary
      pfam12816
      Location:83 → 265
      Vps8; Golgi CORVET complex core vacuolar protein 8
      pfam13639
      Location:727 → 760
      zf-RING_2; Ring finger domain

    14. XM_006713556.5 → XP_006713619.1  vacuolar protein sorting-associated protein 8 homolog isoform X7

      Conserved Domains (2) summary
      pfam12816
      Location:42 → 224
      Vps8; Golgi CORVET complex core vacuolar protein 8
      pfam13639
      Location:686 → 719
      zf-RING_2; Ring finger domain

    15. XM_011512600.4 → XP_011510902.1  vacuolar protein sorting-associated protein 8 homolog isoform X8

      Related
      ENST00000492449.5
      Conserved Domains (2) summary
      pfam12816
      Location:35 → 217
      Vps8; Golgi CORVET complex core vacuolar protein 8
      pfam13639
      Location:679 → 712
      zf-RING_2; Ring finger domain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060927.1 Alternate T2T-CHM13v2.0

      Range
      187627968..187868623
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054345891.1 → XP_054201866.1  vacuolar protein sorting-associated protein 8 homolog isoform X2

      UniProtKB/TrEMBL
      C9JJN9

    2. XM_054345886.1 → XP_054201861.1  vacuolar protein sorting-associated protein 8 homolog isoform X1

      UniProtKB/TrEMBL
      C9JJN9

    3. XM_054345889.1 → XP_054201864.1  vacuolar protein sorting-associated protein 8 homolog isoform X2

      UniProtKB/TrEMBL
      C9JJN9

    4. XM_054345890.1 → XP_054201865.1  vacuolar protein sorting-associated protein 8 homolog isoform X2

      UniProtKB/TrEMBL
      C9JJN9

    5. XM_054345894.1 → XP_054201869.1  vacuolar protein sorting-associated protein 8 homolog isoform X4

      UniProtKB/TrEMBL
      B3KPR6

    6. XM_054345895.1 → XP_054201870.1  vacuolar protein sorting-associated protein 8 homolog isoform X5

      UniProtKB/TrEMBL
      B3KPR6

    7. XM_054345899.1 → XP_054201874.1  vacuolar protein sorting-associated protein 8 homolog isoform X9

    8. XM_054345900.1 → XP_054201875.1  vacuolar protein sorting-associated protein 8 homolog isoform X10

    9. XM_054345887.1 → XP_054201862.1  vacuolar protein sorting-associated protein 8 homolog isoform X1

      UniProtKB/TrEMBL
      C9JJN9

    10. XM_054345892.1 → XP_054201867.1  vacuolar protein sorting-associated protein 8 homolog isoform X2

      UniProtKB/TrEMBL
      C9JJN9

    11. XM_054345888.1 → XP_054201863.1  vacuolar protein sorting-associated protein 8 homolog isoform X1

      UniProtKB/TrEMBL
      C9JJN9

    12. XM_054345893.1 → XP_054201868.1  vacuolar protein sorting-associated protein 8 homolog isoform X3

      UniProtKB/TrEMBL
      C9JJN9

    13. XM_054345896.1 → XP_054201871.1  vacuolar protein sorting-associated protein 8 homolog isoform X6

    14. XM_054345897.1 → XP_054201872.1  vacuolar protein sorting-associated protein 8 homolog isoform X7

    15. XM_054345898.1 → XP_054201873.1  vacuolar protein sorting-associated protein 8 homolog isoform X8

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8N3P4.3 GenPept UniProtKB/Swiss-Prot:Q8N3P4

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