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    Golph3l golgi phosphoprotein 3-like [ Mus musculus (house mouse) ]

    Gene ID: 229593, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Golph3lprovided by MGI
    Official Full Name
    golgi phosphoprotein 3-likeprovided by MGI
    Primary source
    MGI:MGI:1917129
    See related
    Ensembl:ENSMUSG00000046519 AllianceGenome:MGI:1917129
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gpp34r; 2010204I15Rik
    Summary
    Predicted to enable cargo adaptor activity and phosphatidylinositol-4-phosphate binding activity. Predicted to be involved in several processes, including Golgi vesicle transport; positive regulation of protein secretion; and protein targeting to Golgi apparatus. Predicted to be located in Golgi apparatus. Predicted to be active in Golgi cisterna; cytosol; and trans-Golgi network. Orthologous to human GOLPH3L (golgi phosphoprotein 3 like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in colon adult (RPKM 12.9), liver E14 (RPKM 11.0) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Golph3l in Genome Data Viewer
    Location:
    3 F2.1; 3 40.74 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (95496280..95526553)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (95588915..95619247)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene high mobility group box 1, pseudogene 5 Neighboring gene cathepsin S Neighboring gene HORMA domain containing 1 Neighboring gene STARR-positive B cell enhancer mm9_chr3:95392515-95392816 Neighboring gene predicted gene, 40097 Neighboring gene ribosomal protein S10, pseudogene 1 Neighboring gene endosulfine alpha

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
    2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC28597

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cargo adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cargo adaptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables phosphatidylinositol-4-phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidylinositol-4-phosphate binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables phosphatidylinositol-4-phosphate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in Golgi organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in Golgi organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in Golgi to plasma membrane protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in Golgi vesicle budding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of protein secretion ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of protein secretion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein targeting to Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein targeting to Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in Golgi cisterna IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi cisterna ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in Golgi cisterna membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in trans-Golgi network ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    Golgi phosphoprotein 3-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001177669.2 → NP_001171140.2  Golgi phosphoprotein 3-like isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC092203, AC092479
      Consensus CDS
      CCDS57235.1
      Related
      ENSMUSP00000135406.3, ENSMUST00000177389.8

    2. NM_001177670.2 → NP_001171141.2  Golgi phosphoprotein 3-like isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC092203, AC092479
      Consensus CDS
      CCDS57234.1
      Related
      ENSMUSP00000134804.3, ENSMUST00000176755.8

    3. NM_001404119.1 → NP_001391048.1  Golgi phosphoprotein 3-like isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC092203, AC092479
      UniProtKB/Swiss-Prot
      Q3TIX2, Q3TV24, Q8R088
      UniProtKB/TrEMBL
      H3BJ07

    4. NM_001404120.1 → NP_001391049.1  Golgi phosphoprotein 3-like isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC092203, AC092479
      UniProtKB/Swiss-Prot
      Q3TIX2, Q3TV24, Q8R088
      UniProtKB/TrEMBL
      H3BJ07

    5. NM_001404121.1 → NP_001391050.1  Golgi phosphoprotein 3-like isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC092203, AC092479
      UniProtKB/TrEMBL
      H3BJ82
      Related
      ENSMUSP00000134885.3, ENSMUST00000176674.8

    6. NM_001404122.1 → NP_001391051.1  Golgi phosphoprotein 3-like isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC092203, AC092479

    7. NM_001404123.1 → NP_001391052.1  Golgi phosphoprotein 3-like isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC092203, AC092479
      UniProtKB/TrEMBL
      H3BJN5
      Related
      ENSMUSP00000135056.3, ENSMUST00000176541.2

    8. NM_146133.4 → NP_666245.3  Golgi phosphoprotein 3-like isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC092203, AC092479
      Consensus CDS
      CCDS17616.2
      UniProtKB/Swiss-Prot
      Q3TIX2, Q3TV24, Q8R088
      UniProtKB/TrEMBL
      H3BJ07
      Related
      ENSMUSP00000134799.3, ENSMUST00000177390.8

    RNA

    1. NR_175818.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC092203, AC092479

    2. NR_175819.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC092203, AC092479

    3. NR_175821.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC092203, AC092479

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      95496280..95526553
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8R088.1 GenPept UniProtKB/Swiss-Prot:Q8R088

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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