DAL2 allantoicase [Saccharomyces cerevisiae S288C] - Gene

Summary

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Official Symbol: DAL2
Official Full Name: allantoicase
Primary source: SGD:S000001468
Locus tag: YIR029W
See related: AllianceGenome:SGD:S000001468; FungiDB:YIR029W; VEuPathDB:YIR029W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: ALC1
Summary: Enables allantoicase activity. Involved in allantoin catabolic process. Orthologous to human ALLC (allantoicase). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See DAL2 in Genome Data Viewer

Location:: chromosome: IX

Exon count:: 1

Sequence:: Chromosome: IX; NC_001141.2 (410807..411838)

Chromosome IX - NC_001141.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001141.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The YIR029W structure reported here represents the first allantoicase, whose structure has been determined by X-ray crystallography using the MAD method.
Title: Crystal structure of an allantoicase (YIR029W) from Saccharomyces cerevisiae at 2.4 A resolution.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables allantoicase activity	IBA Inferred from Biological aspect of Ancestor more info
enables allantoicase activity	IDA Inferred from Direct Assay more info	PubMed
enables allantoicase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in allantoin catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in allantoin catabolic process	IEA Inferred from Electronic Annotation more info
involved_in allantoin catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in purine nucleobase metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: allantoicase

NP_012295.1

EC 3.5.3.4

Allantoicase; converts allantoate to urea and ureidoglycolate in the second step of allantoin degradation; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001141.2 Reference assembly

Range

410807..411838

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001179551.1 → NP_012295.1 TPA: allantoicase [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_012295.1

Status: REVIEWED

UniProtKB/Swiss-Prot

D6VVW0, P25335

UniProtKB/TrEMBL

A6ZVU9, C7GLS7, C8ZAT0, G2WFV7, N1P1T4

Conserved Domains (1) summary

cl27253
Location:1 → 343

Alc; Allantoicase [Nucleotide transport and metabolism]