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    Sdb SAXO downstream of blistered [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36573, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Sdbprovided by FlyBase
    Official Full Name
    SAXO downstream of blisteredprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050069
    Locus tag
    Dmel_CG30069
    See related
    AllianceGenome:FB:FBgn0050069
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13017; CG30069; CG8381; Dmel\CG30069
    Summary
    Predicted to enable microtubule binding activity. Involved in cytoplasmic microtubule organization and imaginal disc-derived wing morphogenesis. Predicted to be active in microtubule cytoskeleton and sperm flagellum. Is expressed in adult head; embryonic abdominal segment; and posterior spiracle primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Sdb in Genome Data Viewer
    Location:
    50E1-50E3; 2-69 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14185204..14198368)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10072709..10085873)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Receptor expression enhancing protein B Neighboring gene mitochondrial ribosomal protein S16 Neighboring gene combgap Neighboring gene Vesicular GABA Transporter Neighboring gene Sox box protein 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Atypical laminin spots and pull-generated microtubule-actin projections mediate Drosophila wing adhesion. Sun T, et al. Cell Rep, 2021 Sep 7. PMID 34496252
    2. Cellular analysis of newly identified Hox downstream genes in Drosophila. Zhai Z, et al. Eur J Cell Biol, 2010 Feb-Mar. PMID 20018403
    3. Functional analysis of genes differentially expressed in the Drosophila wing disc: role of transcripts enriched in the wing region. Jacobsen TL, et al. Genetics, 2006 Dec. PMID 17028348, Free PMC Article
    4. Paternal diet affects differential gene expression, but not sperm competition, in sons. Zajitschek F, et al. Biol Lett, 2017 Feb. PMID 28202685, Free PMC Article
    5. The BET protein FSH functionally interacts with ASH1 to orchestrate global gene activity in Drosophila. Kockmann T, et al. Genome Biol, 2013 Feb 25. PMID 23442797, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic microtubule organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in imaginal disc-derived wing morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in wing disc development IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in axonemal microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in sperm flagellum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SAXO downstream of blistered
    Names
    CG30069-PA
    Sdb-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      14185204..14198368
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137093.5 → NP_610937.4  SAXO downstream of blistered [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610937.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z9M5
      Conserved Domains (1) summary
      COG3210
      Location:3607 → 3947
      FhaB; Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z9M5 A1Z9M5
    Q95TJ2 Q95TJ2

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