U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    JJJ2 Jjj2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853277, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    JJJ2
    Official Full Name
    Jjj2p
    Primary source
    SGD:S000003698
    Locus tag
    YJL162C
    See related
    AllianceGenome:SGD:S000003698; FungiDB:YJL162C; VEuPathDB:YJL162C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable unfolded protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding and protein refolding. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See JJJ2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (113878..115629, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene cAMP-dependent protein kinase catalytic subunit TPK1 Neighboring gene uncharacterized protein Neighboring gene tRNA-Glu Neighboring gene Fmp33p

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Synthetic lethal interactions in yeast reveal functional roles of J protein co-chaperones. Gillies AT, et al. Mol Biosyst, 2012 Nov. PMID 22851130, Free PMC Article
    2. A targeted analysis of cellular chaperones reveals contrasting roles for heat shock protein 70 in flock house virus RNA replication. Weeks SA, et al. J Virol, 2010 Jan. PMID 19828623, Free PMC Article
    3. Swa2, the yeast homolog of mammalian auxilin, is specifically required for the propagation of the prion variant [URE3-1]. Troisi EM, et al. Mol Microbiol, 2015 Sep. PMID 26031938, Free PMC Article
    4. Quantitative analysis of chaperone network throughput in budding yeast. Brownridge P, et al. Proteomics, 2013 Apr. PMID 23420633, Free PMC Article
    5. Lifespan Control by Redox-Dependent Recruitment of Chaperones to Misfolded Proteins. Hanzén S, et al. Cell, 2016 Jun 30. PMID 27264606

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in chaperone cofactor-dependent protein refolding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein refolding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Jjj2p
    NP_012373.2
    • hypothetical protein; contains a J-domain, which is a region with homology to the E. coli DnaJ protein

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      113878..115629 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181595.1 → NP_012373.2  TPA: Jjj2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012373.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6ZQH0, D6VW25, P46997
      UniProtKB/TrEMBL
      C7GRZ0, G2WGL1
      Conserved Domains (1) summary
      pfam00226
      Location:13 → 74
      DnaJ; DnaJ domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P46997.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools