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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_003747.3 → NP_003738.2 poly [ADP-ribose] polymerase tankyrase-1
See identical proteins and their annotated locations for NP_003738.2
Status: VALIDATED
- Source sequence(s)
-
AC021242, AC103834, AC103877, AC104052
- Consensus CDS
-
CCDS5974.1
- UniProtKB/Swiss-Prot
- O95271, O95272, Q4G0F2, Q59FX0
- UniProtKB/TrEMBL
-
E7EQ52
- Related
- ENSP00000311579.6, ENST00000310430.11
- Conserved Domains (8) summary
-
- cd09524
Location:1024 → 1089
- SAM_tankyrase1,2; SAM domain of tankyrase1,2 subfamily
- smart00454
Location:1030 → 1087
- SAM; Sterile alpha motif
- cd00204
Location:676 → 801
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- cd01438
Location:1091 → 1313
- tankyrase_like; Tankyrases interact with the telomere reverse transcriptase complex (TERT). Tankyrase 1 poly-ADP-ribosylates Telomere Repeat Binding Factor 1 (TRF1) while Tankyrase 2 can poly-ADP-ribosylate itself or TRF1. The tankyrases also contain multiple ankyrin ...
- pfam00644
Location:1105 → 1308
- PARP; Poly(ADP-ribose) polymerase catalytic domain
- pfam12796
Location:688 → 780
- Ank_2; Ankyrin repeats (3 copies)
- pfam13637
Location:803 → 857
- Ank_4; Ankyrin repeats (many copies)
- sd00045
Location:371 → 399
- ANK; ANK repeat [structural motif]
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000008.11 Reference GRCh38.p14 Primary Assembly
- Range
-
9555912..9782346
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011543845.4 → XP_011542147.1 poly [ADP-ribose] polymerase tankyrase-1 isoform X1
See identical proteins and their annotated locations for XP_011542147.1
- UniProtKB/TrEMBL
- E7EQ52, H0YAW5
- Related
- ENSP00000428185.2, ENST00000517770.2
- Conserved Domains (6) summary
-
- PTZ00322
Location:177 → 269
- PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
- PHA02876
Location:231 → 616
- PHA02876; ankyrin repeat protein; Provisional
- cd09524
Location:1024 → 1089
- SAM_tankyrase1,2; SAM domain of tankyrase1,2 subfamily
- PHA03095
Location:652 → 976
- PHA03095; ankyrin-like protein; Provisional
- cd01438
Location:1091 → 1299
- tankyrase_like; Tankyrases interact with the telomere reverse transcriptase complex (TERT). Tankyrase 1 poly-ADP-ribosylates Telomere Repeat Binding Factor 1 (TRF1) while Tankyrase 2 can poly-ADP-ribosylate itself or TRF1. The tankyrases also contain multiple ankyrin ...
- sd00045
Location:371 → 399
- ANK; ANK repeat [structural motif]
-
XM_011543846.4 → XP_011542148.1 poly [ADP-ribose] polymerase tankyrase-1 isoform X2
- UniProtKB/TrEMBL
-
E7EQ52
- Conserved Domains (6) summary
-
- PTZ00322
Location:177 → 269
- PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
- PHA02876
Location:231 → 616
- PHA02876; ankyrin repeat protein; Provisional
- cd09524
Location:1024 → 1089
- SAM_tankyrase1,2; SAM domain of tankyrase1,2 subfamily
- PHA03095
Location:652 → 976
- PHA03095; ankyrin-like protein; Provisional
- cd01438
Location:1091 → 1299
- tankyrase_like; Tankyrases interact with the telomere reverse transcriptase complex (TERT). Tankyrase 1 poly-ADP-ribosylates Telomere Repeat Binding Factor 1 (TRF1) while Tankyrase 2 can poly-ADP-ribosylate itself or TRF1. The tankyrases also contain multiple ankyrin ...
- sd00045
Location:371 → 399
- ANK; ANK repeat [structural motif]
Reference GRCh38.p14 PATCHES
Genomic
-
NW_018654717.1 Reference GRCh38.p14 PATCHES
- Range
-
3566718..3795557 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054332271.1 → XP_054188246.1 poly [ADP-ribose] polymerase tankyrase-1 isoform X3
- UniProtKB/TrEMBL
-
E7EQ52
-
XM_054332273.1 → XP_054188248.1 poly [ADP-ribose] polymerase tankyrase-1 isoform X5
- UniProtKB/TrEMBL
-
E7EQ52
-
XM_054332272.1 → XP_054188247.1 poly [ADP-ribose] polymerase tankyrase-1 isoform X4
-
XM_054332270.1 → XP_054188245.1 poly [ADP-ribose] polymerase tankyrase-1 isoform X2
- UniProtKB/TrEMBL
-
E7EQ52
-
XM_054332269.1 → XP_054188244.1 poly [ADP-ribose] polymerase tankyrase-1 isoform X1
- UniProtKB/TrEMBL
- E7EQ52, H0YAW5
Alternate T2T-CHM13v2.0
Genomic
-
NC_060932.1 Alternate T2T-CHM13v2.0
- Range
-
9959097..10187973 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054361432.1 → XP_054217407.1 poly [ADP-ribose] polymerase tankyrase-1 isoform X6
- UniProtKB/TrEMBL
-
E7EQ52
-
XM_054361434.1 → XP_054217409.1 poly [ADP-ribose] polymerase tankyrase-1 isoform X8
- UniProtKB/TrEMBL
-
E7EQ52
-
XM_054361433.1 → XP_054217408.1 poly [ADP-ribose] polymerase tankyrase-1 isoform X7
-
XM_054361431.1 → XP_054217406.1 poly [ADP-ribose] polymerase tankyrase-1 isoform X2
- UniProtKB/TrEMBL
-
E7EQ52
-
XM_054361430.1 → XP_054217405.1 poly [ADP-ribose] polymerase tankyrase-1 isoform X1
- UniProtKB/TrEMBL
- E7EQ52, H0YAW5