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    PST1 Pst1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851625, updated on 9-Dec-2024

    Summary

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    Official Symbol
    PST1
    Official Full Name
    Pst1p
    Primary source
    SGD:S000002462
    Locus tag
    YDR055W
    See related
    AllianceGenome:SGD:S000002462; FungiDB:YDR055W; VEuPathDB:YDR055W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    HPF2
    Summary
    Involved in fungal-type cell wall organization. Located in fungal-type cell wall and plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See PST1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (563527..564861)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene protein serine/threonine kinase activating protein DBF4 Neighboring gene SCF E2 ubiquitin-protein ligase catalytic subunit CDC34 Neighboring gene Emc10p Neighboring gene Yos9p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A yeast glycoprotein shows high-affinity binding to the broadly neutralizing human immunodeficiency virus antibody 2G12 and inhibits gp120 interactions with 2G12 and DC-SIGN. Luallen RJ, et al. J Virol, 2009 May. PMID 19264785, Free PMC Article
    2. PST1 and ECM33 encode two yeast cell surface GPI proteins important for cell wall integrity. Pardo M, et al. Microbiology (Reading), 2004 Dec. PMID 15583168
    3. Two-dimensional analysis of proteins secreted by Saccharomyces cerevisiae regenerating protoplasts: a novel approach to study the cell wall. Pardo M, et al. Yeast, 1999 Apr. PMID 10234784
    4. Reducing haziness in white wine by overexpression of Saccharomyces cerevisiae genes YOL155c and YDR055w. Brown SL, et al. Appl Microbiol Biotechnol, 2007 Jan. PMID 17024473
    5. Hpf2 glycan structure is critical for protection against protein haze formation in white wine. Schmidt SA, et al. J Agric Food Chem, 2009 Apr 22. PMID 19301818

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. important for cell wall integrity, may partially substitute for Ecm33
      Title: PST1 and ECM33 encode two yeast cell surface GPI proteins important for cell wall integrity.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in fungal-type cell wall organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in fungal-type vacuole HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Pst1p
    NP_010340.1
    • Cell wall protein that contains a putative GPI-attachment site; secreted by regenerating protoplasts; up-regulated by activation of the cell integrity pathway, as mediated by Rlm1p; upregulated by cell wall damage via disruption of FKS1; PST1 has a paralog, ECM33, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      563527..564861
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180363.1 → NP_010340.1  TPA: Pst1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010340.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6ZY20, D6VS41, Q12355
      UniProtKB/TrEMBL
      B3LGL4, C7GT96, G2WAF9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12355.1

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