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    Plac1 placental specific protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 56096, updated on 9-Dec-2024

    Summary

    Official Symbol
    Plac1provided by MGI
    Official Full Name
    placental specific protein 1provided by MGI
    Primary source
    MGI:MGI:1926287
    See related
    Ensembl:ENSMUSG00000061082 AllianceGenome:MGI:1926287
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Epcs26; Oosp2l; DXWsu72e
    Summary
    Involved in placenta development. Acts upstream of or within spongiotrophoblast layer developmental growth. Predicted to be located in extracellular region. Is expressed in several structures, including body wall mesenchyme; brain; extraembryonic component; genitourinary system; and lung. Orthologous to human PLAC1 (placenta enriched 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward placenta adult (RPKM 67.5) See more
    Orthologs
    NEW
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    Genomic context

    See Plac1 in Genome Data Viewer
    Location:
    X A5; X 29.31 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (52158870..52328969, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (53069993..53240110, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized LOC119919412 Neighboring gene STARR-seq mESC enhancer starr_47192 Neighboring gene Mir503, Mir351, and Mir322 host gene Neighboring gene microRNA 503 Neighboring gene microRNA 322 Neighboring gene predicted gene, 35988 Neighboring gene PABIR family member 2 Neighboring gene PABIR family member 3 Neighboring gene ribosomal protein L13 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (3)  1 citation

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in placenta development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    acts_upstream_of_or_within spongiotrophoblast layer developmental growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in extracellular region TAS
    Traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    placenta-specific protein 1
    Names
    ectoplacental cone, invasive trophoblast giant cells, extraembryonic ectoderm and chorion sequence 26

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357802.2NP_001344731.1  placenta-specific protein 1 precursor

      Status: VALIDATED

      Source sequence(s)
      BX649621, BX679673, BX682227
      Consensus CDS
      CCDS30128.1
      UniProtKB/Swiss-Prot
      Q3UKT4, Q80WW3, Q9JI83
      Related
      ENSMUSP00000074404.3, ENSMUST00000074861.9
      Conserved Domains (1) summary
      pfam00100
      Location:30121
      Zona_pellucida; Zona pellucida-like domain
    2. NM_001426319.1NP_001413248.1  placenta-specific protein 1 precursor

      Status: VALIDATED

      Source sequence(s)
      BX649621, BX679673, BX682227
      UniProtKB/Swiss-Prot
      Q3UKT4, Q80WW3, Q9JI83
      Related
      ENSMUSP00000133862.2, ENSMUST00000174390.2
    3. NM_019538.5NP_062411.1  placenta-specific protein 1 precursor

      See identical proteins and their annotated locations for NP_062411.1

      Status: VALIDATED

      Source sequence(s)
      AK005501, BC051666
      Consensus CDS
      CCDS30128.1
      UniProtKB/Swiss-Prot
      Q3UKT4, Q80WW3, Q9JI83
      Related
      ENSMUSP00000110492.3, ENSMUST00000114843.9
      Conserved Domains (1) summary
      pfam00100
      Location:30121
      Zona_pellucida; Zona pellucida-like domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      52158870..52328969 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011251016.3XP_011249318.1  placenta-specific protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011249318.1

      UniProtKB/Swiss-Prot
      Q3UKT4, Q80WW3, Q9JI83
      Conserved Domains (1) summary
      pfam00100
      Location:30121
      Zona_pellucida; Zona pellucida-like domain