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    Lcn5 lipocalin 5 [ Mus musculus (house mouse) ]

    Gene ID: 13863, updated on 9-Dec-2024

    Summary

    Official Symbol
    Lcn5provided by MGI
    Official Full Name
    lipocalin 5provided by MGI
    Primary source
    MGI:MGI:1277241
    See related
    Ensembl:ENSMUSG00000026937 AllianceGenome:MGI:1277241
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Erabp; MEP10; E-RABP
    Summary
    This gene encodes a small secreted protein that is expressed in the epididymis and binds retinoic acid. The precursor protein is processed into both a longer major form and a shorter minor form. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]
    Expression
    Restricted expression toward genital fat pad adult (RPKM 713.9) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Lcn5 in Genome Data Viewer
    Location:
    2 A3; 2 17.68 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (25547944..25552242)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (25657932..25662230)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene lipocalin 15 Neighboring gene lipocalin 8 Neighboring gene lipocalin 6 Neighboring gene lipocalin 10

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General protein information

    Preferred Names
    epididymal-specific lipocalin-5
    Names
    epididymal retinoic acid binding protein
    epididymal secretory protein 10

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042630.2NP_001036095.1  epididymal-specific lipocalin-5 isoform b precursor

      See identical proteins and their annotated locations for NP_001036095.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (b) has a shorter C-terminus, compared to isoform a.
      Source sequence(s)
      AK136629, AK162355
      Consensus CDS
      CCDS38078.1
      UniProtKB/Swiss-Prot
      A2AJB7
      Related
      ENSMUSP00000097888.4, ENSMUST00000100313.4
      Conserved Domains (2) summary
      pfam00061
      Location:41179
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family
      cl21528
      Location:3148
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family
    2. NM_001276257.1NP_001263186.1  epididymal-specific lipocalin-5 isoform c precursor

      See identical proteins and their annotated locations for NP_001263186.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (c) is the same length but has a distinct C-terminus, compared to isoform a.
      Source sequence(s)
      AK136629, AV379690
      Consensus CDS
      CCDS71003.1
      UniProtKB/Swiss-Prot
      A2AJB7
      Related
      ENSMUSP00000097887.4, ENSMUST00000100312.10
      Conserved Domains (2) summary
      pfam00061
      Location:41179
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family
      cl21528
      Location:3148
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family
    3. NM_007947.3NP_031973.2  epididymal-specific lipocalin-5 isoform a precursor

      See identical proteins and their annotated locations for NP_031973.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the shortest transcript and encodes isoform a.
      Source sequence(s)
      AK021014, AK136629, AV379690
      Consensus CDS
      CCDS38079.1
      UniProtKB/Swiss-Prot
      A2AJB7, O88787, Q3TS05, Q3UW42, Q9R2C6
      Related
      ENSMUSP00000028306.7, ENSMUST00000028306.13
      Conserved Domains (2) summary
      pfam00061
      Location:41179
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family
      cl21528
      Location:3148
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      25547944..25552242
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006497666.4XP_006497729.1  epididymal-specific lipocalin-5 isoform X2

      Conserved Domains (1) summary
      cl10502
      Location:31189
      lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family
    2. XM_006497665.1XP_006497728.1  epididymal-specific lipocalin-5 isoform X1

      Conserved Domains (1) summary
      cl10502
      Location:31182
      lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family
    3. XM_006497669.1XP_006497732.1  epididymal-specific lipocalin-5 isoform X5

      Conserved Domains (1) summary
      cl10502
      Location:31147
      lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family
    4. XM_006497668.2XP_006497731.1  epididymal-specific lipocalin-5 isoform X4

      See identical proteins and their annotated locations for XP_006497731.1

      Conserved Domains (1) summary
      cl10502
      Location:31189
      lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family
    5. XM_006497667.3XP_006497730.1  epididymal-specific lipocalin-5 isoform X3

      See identical proteins and their annotated locations for XP_006497730.1

      Conserved Domains (1) summary
      cl10502
      Location:31189
      lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family