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    Klrg1 killer cell lectin-like receptor subfamily G, member 1 [ Mus musculus (house mouse) ]

    Gene ID: 50928, updated on 9-Dec-2024

    Summary

    Official Symbol
    Klrg1provided by MGI
    Official Full Name
    killer cell lectin-like receptor subfamily G, member 1provided by MGI
    Primary source
    MGI:MGI:1355294
    See related
    Ensembl:ENSMUSG00000030114 AllianceGenome:MGI:1355294
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MAFA; 2F1-Ag; MAFA-L
    Summary
    Predicted to enable carbohydrate binding activity. Predicted to be involved in innate immune response. Predicted to act upstream of or within cell surface receptor signaling pathway. Predicted to be located in intracellular membrane-bounded organelle. Orthologous to human KLRG1 (killer cell lectin like receptor G1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Genomic context

    See Klrg1 in Genome Data Viewer
    Location:
    6 F1; 6 57.52 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (122247555..122259792, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (122270596..122282833, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene murinoglobulin pseudogene Neighboring gene murinoglobulin, pseudogene 1 Neighboring gene predicted gene, 46974 Neighboring gene STARR-positive B cell enhancer ABC_E6483 Neighboring gene predicted gene, 53340 Neighboring gene predicted gene 6637

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General protein information

    Preferred Names
    killer cell lectin-like receptor subfamily G member 1
    Names
    mast cell function-associated antigen 2F1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_016970.1NP_058666.1  killer cell lectin-like receptor subfamily G member 1

      See identical proteins and their annotated locations for NP_058666.1

      Status: PROVISIONAL

      Source sequence(s)
      AF097357
      Consensus CDS
      CCDS20492.1
      UniProtKB/Swiss-Prot
      O88713, Q3T1F0
      Related
      ENSMUSP00000032207.9, ENSMUST00000032207.9
      Conserved Domains (1) summary
      cd03593
      Location:75185
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      122247555..122259792 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)