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    Rabl6 RAB, member RAS oncogene family-like 6 [ Mus musculus (house mouse) ]

    Gene ID: 227624, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rabl6provided by MGI
    Official Full Name
    RAB, member RAS oncogene family-like 6provided by MGI
    Primary source
    MGI:MGI:2442633
    See related
    Ensembl:ENSMUSG00000015087 AllianceGenome:MGI:2442633
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    parf; Rbel1; Rbel1a; Rbel1b; B230208H17Rik
    Summary
    Predicted to enable GTP binding activity. Predicted to be located in centrosome and cytoplasm. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; hemolymphoid system gland; and nervous system. Orthologous to human RABL6 (RAB, member RAS oncogene family like 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 56.2), ovary adult (RPKM 45.2) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Rabl6 in Genome Data Viewer
    Location:
    2 A3; 2 17.46 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (25473029..25498493, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (25583017..25608481, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene MAM domain containing 4 Neighboring gene STARR-positive B cell enhancer ABC_E1582 Neighboring gene phosphohistidine phosphatase 1 Neighboring gene apical junction component 1 Neighboring gene coiled-coil domain containing 183 Neighboring gene ficolin A, opposite strand Neighboring gene transmembrane protein 141

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTP binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    rab-like protein 6
    Names
    RAB, member of RAS oncogene family-like 6
    putative GTP-binding protein Parf
    rab-like protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024616.2NP_001019787.2  rab-like protein 6

      See identical proteins and their annotated locations for NP_001019787.2

      Status: VALIDATED

      Source sequence(s)
      BC085507, BX514513, BY130272
      Consensus CDS
      CCDS38076.1
      UniProtKB/Swiss-Prot
      A2AJB0, Q3TAT5, Q3TRU4, Q5U3K5, Q6PDP8, Q8BFS4, Q8CGJ9
      Related
      ENSMUSP00000058746.9, ENSMUST00000058137.9
      Conserved Domains (2) summary
      pfam00071
      Location:45221
      Ras; Ras family
      cl21455
      Location:44221
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      25473029..25498493 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)