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    Ssbp2 single-stranded DNA binding protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 66970, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ssbp2provided by MGI
    Official Full Name
    single-stranded DNA binding protein 2provided by MGI
    Primary source
    MGI:MGI:1914220
    See related
    Ensembl:ENSMUSG00000003992 AllianceGenome:MGI:1914220
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SSDP2; Hspc116; 1500004K09Rik; 2310079I02Rik; 9330163K02Rik; A830008M03Rik
    Summary
    Predicted to enable single-stranded DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including adipose tissue; alimentary system; central nervous system; genitourinary system; and limb. Orthologous to human SSBP2 (single stranded DNA binding protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in CNS E18 (RPKM 14.2), whole brain E14.5 (RPKM 8.6) and 18 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ssbp2 in Genome Data Viewer
    Location:
    13 C3; 13 47.43 cM
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (91608449..91854299)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (91460305..91706175)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41014 Neighboring gene heterogeneous nuclear ribonucleoprotein K pseudogene Neighboring gene RIKEN cDNA A830009L08 gene Neighboring gene STARR-seq mESC enhancer starr_35251 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:91510584-91510802 Neighboring gene STARR-seq mESC enhancer starr_35253 Neighboring gene STARR-positive B cell enhancer mm9_chr13:91600311-91600612 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:91680694-91680899 Neighboring gene predicted gene, 41016 Neighboring gene STARR-positive B cell enhancer mm9_chr13:91775680-91775980 Neighboring gene STARR-positive B cell enhancer mm9_chr13:91776398-91776699 Neighboring gene STARR-seq mESC enhancer starr_35255 Neighboring gene RIKEN cDNA 4833422C13 gene Neighboring gene predicted gene, 22778 Neighboring gene STARR-seq mESC enhancer starr_35256 Neighboring gene acyl-CoA thioesterase 12

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables single-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    single-stranded DNA-binding protein 2
    Names
    sequence-specific single-stranded-DNA-binding protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360775.2NP_001347704.1  single-stranded DNA-binding protein 2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC154320, CT009700
      Conserved Domains (2) summary
      smart00667
      Location:1945
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:83346
      SSDP; Single-stranded DNA binding protein, SSDP
    2. NM_001360776.2NP_001347705.1  single-stranded DNA-binding protein 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC154320, CT009700
      Conserved Domains (2) summary
      smart00667
      Location:1945
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:92316
      SSDP; Single-stranded DNA binding protein, SSDP
    3. NM_024186.6NP_077148.1  single-stranded DNA-binding protein 2 isoform 1

      See identical proteins and their annotated locations for NP_077148.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) lacks an alternate in-frame exon in the 5' coding region, compared to variant 2. The resulting isoform (1) lacks an internal segment, compared to isoform 2.
      Source sequence(s)
      AC154320, CT009700
      Consensus CDS
      CCDS26676.1
      UniProtKB/Swiss-Prot
      Q9CYZ8
      Related
      ENSMUSP00000037115.9, ENSMUST00000042122.15
      Conserved Domains (2) summary
      smart00667
      Location:1945
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:92308
      SSDP; Single-stranded DNA binding protein, SSDP
    4. NM_024272.5NP_077234.2  single-stranded DNA-binding protein 2 isoform 2

      See identical proteins and their annotated locations for NP_077234.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) represents the longest transcript and encodes isoform 2.
      Source sequence(s)
      AC154320, CT009700
      Consensus CDS
      CCDS26677.1
      UniProtKB/Swiss-Prot
      B1B188, Q99LX9, Q9CYZ8
      UniProtKB/TrEMBL
      Q540I3
      Related
      ENSMUSP00000004094.9, ENSMUST00000004094.15
      Conserved Domains (2) summary
      smart00667
      Location:1945
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:83338
      SSDP; Single-stranded DNA binding protein, SSDP

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      91608449..91854299
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030247373.2XP_030103233.1  single-stranded DNA-binding protein 2 isoform X12

      Conserved Domains (1) summary
      pfam04503
      Location:1232
      SSDP; Single-stranded DNA binding protein, SSDP
    2. XM_030247371.2XP_030103231.1  single-stranded DNA-binding protein 2 isoform X11

      Conserved Domains (1) summary
      pfam04503
      Location:1240
      SSDP; Single-stranded DNA binding protein, SSDP
    3. XM_030247377.2XP_030103237.1  single-stranded DNA-binding protein 2 isoform X14

      Conserved Domains (1) summary
      pfam04503
      Location:17212
      SSDP; Single-stranded DNA binding protein, SSDP
    4. XM_030247376.2XP_030103236.1  single-stranded DNA-binding protein 2 isoform X13

      Conserved Domains (1) summary
      pfam04503
      Location:17220
      SSDP; Single-stranded DNA binding protein, SSDP
    5. XM_006517334.4XP_006517397.1  single-stranded DNA-binding protein 2 isoform X8

      Conserved Domains (1) summary
      pfam04503
      Location:38301
      SSDP; Single-stranded DNA binding protein, SSDP
    6. XM_030247368.2XP_030103228.1  single-stranded DNA-binding protein 2 isoform X10

      Conserved Domains (1) summary
      pfam04503
      Location:47271
      SSDP; Single-stranded DNA binding protein, SSDP
    7. XM_036158126.1XP_036014019.1  single-stranded DNA-binding protein 2 isoform X7

      Conserved Domains (1) summary
      pfam04503
      Location:64319
      SSDP; Single-stranded DNA binding protein, SSDP
    8. XM_030247369.2XP_030103229.1  single-stranded DNA-binding protein 2 isoform X11

      Conserved Domains (1) summary
      pfam04503
      Location:1240
      SSDP; Single-stranded DNA binding protein, SSDP
    9. XM_030247372.2XP_030103232.1  single-stranded DNA-binding protein 2 isoform X11

      Conserved Domains (1) summary
      pfam04503
      Location:1240
      SSDP; Single-stranded DNA binding protein, SSDP
    10. XM_036158129.1XP_036014022.1  single-stranded DNA-binding protein 2 isoform X13

      Conserved Domains (1) summary
      pfam04503
      Location:17220
      SSDP; Single-stranded DNA binding protein, SSDP
    11. XM_030247375.2XP_030103235.1  single-stranded DNA-binding protein 2 isoform X12

      Conserved Domains (1) summary
      pfam04503
      Location:1232
      SSDP; Single-stranded DNA binding protein, SSDP
    12. XM_030247378.2XP_030103238.1  single-stranded DNA-binding protein 2 isoform X14

      Conserved Domains (1) summary
      pfam04503
      Location:17212
      SSDP; Single-stranded DNA binding protein, SSDP
    13. XM_030247367.2XP_030103227.1  single-stranded DNA-binding protein 2 isoform X9

      Conserved Domains (1) summary
      pfam04503
      Location:73289
      SSDP; Single-stranded DNA binding protein, SSDP
    14. XM_011244554.2XP_011242856.1  single-stranded DNA-binding protein 2 isoform X6

      Conserved Domains (1) summary
      pfam04503
      Location:64327
      SSDP; Single-stranded DNA binding protein, SSDP
    15. XM_036158130.1XP_036014023.1  single-stranded DNA-binding protein 2 isoform X14

      Conserved Domains (1) summary
      pfam04503
      Location:17212
      SSDP; Single-stranded DNA binding protein, SSDP
    16. XM_030247374.1XP_030103234.1  single-stranded DNA-binding protein 2 isoform X12

      Conserved Domains (1) summary
      pfam04503
      Location:1232
      SSDP; Single-stranded DNA binding protein, SSDP
    17. XM_036158127.1XP_036014020.1  single-stranded DNA-binding protein 2 isoform X11

      Conserved Domains (1) summary
      pfam04503
      Location:1240
      SSDP; Single-stranded DNA binding protein, SSDP
    18. XM_036158128.1XP_036014021.1  single-stranded DNA-binding protein 2 isoform X13

      Conserved Domains (1) summary
      pfam04503
      Location:17220
      SSDP; Single-stranded DNA binding protein, SSDP
    19. XM_036158131.1XP_036014024.1  single-stranded DNA-binding protein 2 isoform X14

      Conserved Domains (1) summary
      pfam04503
      Location:17212
      SSDP; Single-stranded DNA binding protein, SSDP
    20. XM_030247370.2XP_030103230.1  single-stranded DNA-binding protein 2 isoform X11

      Conserved Domains (1) summary
      pfam04503
      Location:1240
      SSDP; Single-stranded DNA binding protein, SSDP
    21. XM_036158125.1XP_036014018.1  single-stranded DNA-binding protein 2 isoform X3

      Conserved Domains (1) summary
      pfam04503
      Location:103337
      SSDP; Single-stranded DNA binding protein, SSDP
    22. XM_006517328.5XP_006517391.1  single-stranded DNA-binding protein 2 isoform X1

      Conserved Domains (1) summary
      pfam04503
      Location:103366
      SSDP; Single-stranded DNA binding protein, SSDP
    23. XM_006517329.4XP_006517392.1  single-stranded DNA-binding protein 2 isoform X2

      Conserved Domains (1) summary
      pfam04503
      Location:103358
      SSDP; Single-stranded DNA binding protein, SSDP
    24. XM_006517332.5XP_006517395.1  single-stranded DNA-binding protein 2 isoform X5

      Conserved Domains (1) summary
      pfam04503
      Location:112328
      SSDP; Single-stranded DNA binding protein, SSDP
    25. XM_011244553.4XP_011242855.1  single-stranded DNA-binding protein 2 isoform X4

      Conserved Domains (1) summary
      pfam04503
      Location:112336
      SSDP; Single-stranded DNA binding protein, SSDP

    RNA

    1. XR_003950464.2 RNA Sequence

    2. XR_004938052.1 RNA Sequence

    3. XR_003950466.2 RNA Sequence

    4. XR_003950463.2 RNA Sequence

    5. XR_003950465.2 RNA Sequence