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    Apol11b apolipoprotein L 11b [ Mus musculus (house mouse) ]

    Gene ID: 328563, updated on 9-Dec-2024

    Summary

    Official Symbol
    Apol11bprovided by MGI
    Official Full Name
    apolipoprotein L 11bprovided by MGI
    Primary source
    MGI:MGI:3036248
    See related
    Ensembl:ENSMUSG00000091694 AllianceGenome:MGI:3036248
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A330102K04Rik
    Summary
    Predicted to enable chloride channel activity and lipid binding activity. Predicted to be located in extracellular space. Predicted to be part of high-density lipoprotein particle and very-low-density lipoprotein particle. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human APOL1 (apolipoprotein L1) and APOL2 (apolipoprotein L2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in spleen adult (RPKM 4.8), liver E14 (RPKM 2.8) and 4 other tissues See more
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    Genomic context

    See Apol11b in Genome Data Viewer
    Location:
    15 E1; 15 36.58 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (77518151..77527486, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (77633951..77643286, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 36245 Neighboring gene apolipoprotein L 7c pseudogene Neighboring gene apolipoprotein L 10C, pseudogene Neighboring gene STARR-seq mESC enhancer starr_39109 Neighboring gene apolipoprotein L 7e Neighboring gene INO80 complex subunit C pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Clone Names

    • MGC175770

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chloride channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables lipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables lipid binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    part_of high-density lipoprotein particle ISO
    Inferred from Sequence Orthology
    more info
     
    part_of very-low-density lipoprotein particle ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001143686.1NP_001137158.1  apolipoprotein L 11b

      Status: VALIDATED

      Source sequence(s)
      AK039744, BB634068, BB653856
      Consensus CDS
      CCDS49662.1
      UniProtKB/TrEMBL
      A6H6I0, E9PUZ0
      Related
      ENSMUSP00000129476.2, ENSMUST00000166623.10
      Conserved Domains (1) summary
      pfam05461
      Location:41288
      ApoL; Apolipoprotein L

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      77518151..77527486 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)