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    Gatad2a GATA zinc finger domain containing 2A [ Mus musculus (house mouse) ]

    Gene ID: 234366, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gatad2aprovided by MGI
    Official Full Name
    GATA zinc finger domain containing 2Aprovided by MGI
    Primary source
    MGI:MGI:2384585
    See related
    Ensembl:ENSMUSG00000036180 AllianceGenome:MGI:2384585
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110066C11Rik
    Summary
    Predicted to enable protein-macromolecule adaptor activity. Acts upstream of or within several processes, including blood vessel development; chordate embryonic development; and embryonic body morphogenesis. Predicted to be located in nucleoplasm. Predicted to be part of NuRD complex. Is expressed in several structures, including brain and enteric nervous system. Orthologous to human GATAD2A (GATA zinc finger domain containing 2A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 31.4), ovary adult (RPKM 26.7) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Gatad2a in Genome Data Viewer
    Location:
    8 B3.3; 8 34.06 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (70359719..70450093, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (69907069..69996402, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33746 Neighboring gene YjeF N-terminal domain containing 3 Neighboring gene STARR-positive B cell enhancer ABC_E10503 Neighboring gene STARR-positive B cell enhancer ABC_E1757 Neighboring gene NADH:ubiquinone oxidoreductase subunit A13 Neighboring gene testis-specific serine kinase 6 Neighboring gene STARR-positive B cell enhancer ABC_E5012 Neighboring gene STARR-positive B cell enhancer ABC_E1367 Neighboring gene STARR-seq mESC enhancer starr_21753 Neighboring gene STARR-seq mESC enhancer starr_21758 Neighboring gene STARR-positive B cell enhancer ABC_E89 Neighboring gene STARR-seq mESC enhancer starr_21762 Neighboring gene nucleoside diphosphate kinase B pseudogene Neighboring gene MAU2 sister chromatid cohesion factor Neighboring gene STARR-positive B cell enhancer ABC_E9314

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC29315, MGC36975

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-macromolecule adaptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-macromolecule adaptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within anterior neuropore closure IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within blood vessel development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in chromatin remodeling ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within embryonic body morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within in utero embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of DNA-templated transcription NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within neural fold formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of DNA-templated transcription NAS
    Non-traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within programmed cell death IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of cell fate specification NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in regulation of stem cell differentiation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of NuRD complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of NuRD complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of NuRD complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of NuRD complex NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    transcriptional repressor p66 alpha
    Names
    GATA zinc finger domain-containing protein 2A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001113346.1NP_001106817.1  transcriptional repressor p66 alpha isoform b

      See identical proteins and their annotated locations for NP_001106817.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform b), compared to isoform a.
      Source sequence(s)
      AC158564, BQ571528, CF726663, CJ166913, CN666280, CV562594, DV651557
      Consensus CDS
      CCDS52567.1
      UniProtKB/Swiss-Prot
      Q8BTQ2, Q8CHY6, Q8VEC9
      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Related
      ENSMUSP00000112164.3, ENSMUST00000116463.4
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:416448
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    2. NM_001286450.1NP_001273379.1  transcriptional repressor p66 alpha isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) uses several alternate splice sites, one of which results in a frameshift, compared to variant 1. This results in a longer protein (isoform d) with a distinct C-terminus, compared to isoform a.
      Source sequence(s)
      AK083473, AK148968, AK160058
      Related
      ENSMUSP00000137386.3, ENSMUST00000177851.9
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl00158
      Location:419452
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    3. NM_145596.4NP_663571.2  transcriptional repressor p66 alpha isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. It encodes isoform a.
      Source sequence(s)
      AK083473, AK148968, AK160058, CA317226
      Consensus CDS
      CCDS22355.1
      UniProtKB/TrEMBL
      A0A1I7Q4G8, E9QMN5
      Related
      ENSMUSP00000070229.5, ENSMUST00000065169.12
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:417450
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      70359719..70450093 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017312722.3XP_017168211.1  transcriptional repressor p66 alpha isoform X16

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:415448
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    2. XM_030243469.2XP_030099329.1  transcriptional repressor p66 alpha isoform X8

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:415448
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    3. XM_017312721.3XP_017168210.1  transcriptional repressor p66 alpha isoform X14

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:416448
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    4. XM_017312720.3XP_017168209.1  transcriptional repressor p66 alpha isoform X13

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:417449
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    5. XM_030243470.2XP_030099330.1  transcriptional repressor p66 alpha isoform X10

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:419452
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    6. XM_030243471.2XP_030099331.1  transcriptional repressor p66 alpha isoform X11

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:419451
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    7. XM_006509636.5XP_006509699.1  transcriptional repressor p66 alpha isoform X3

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:419451
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    8. XM_006509638.5XP_006509701.1  transcriptional repressor p66 alpha isoform X9

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:420453
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    9. XM_036153943.1XP_036009836.1  transcriptional repressor p66 alpha isoform X15

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:416449
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    10. XM_017312719.3XP_017168208.1  transcriptional repressor p66 alpha isoform X7

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:416448
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    11. XM_030243475.2XP_030099335.1  transcriptional repressor p66 alpha isoform X15

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:416449
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    12. XM_036153940.1XP_036009833.1  transcriptional repressor p66 alpha isoform X9

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:420453
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    13. XM_030243474.2XP_030099334.1  transcriptional repressor p66 alpha isoform X14

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:416448
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    14. XM_036153944.1XP_036009837.1  transcriptional repressor p66 alpha isoform X16

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:415448
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    15. XM_036153938.1XP_036009831.1  transcriptional repressor p66 alpha isoform X8

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:415448
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    16. XM_030243472.2XP_030099332.1  transcriptional repressor p66 alpha isoform X13

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:417449
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    17. XM_036153942.1XP_036009835.1  transcriptional repressor p66 alpha isoform X12

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:418451
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    18. XM_030243463.2XP_030099323.1  transcriptional repressor p66 alpha isoform X4

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:418450
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    19. XM_036153941.1XP_036009834.1  transcriptional repressor p66 alpha isoform X10

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:419452
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    20. XM_036153939.1XP_036009832.1  transcriptional repressor p66 alpha isoform X9

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:420453
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    21. XM_030243473.2XP_030099333.1  transcriptional repressor p66 alpha isoform X14

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:416448
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    22. XM_017312716.3XP_017168205.1  transcriptional repressor p66 alpha isoform X1

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:420452
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    23. XM_011242295.4XP_011240597.1  transcriptional repressor p66 alpha isoform X6

      See identical proteins and their annotated locations for XP_011240597.1

      UniProtKB/Swiss-Prot
      Q8BTQ2, Q8CHY6, Q8VEC9
      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Related
      ENSMUSP00000148474.2, ENSMUST00000212478.2
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:416448
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    24. XM_017312718.3XP_017168207.1  transcriptional repressor p66 alpha isoform X2

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:419452
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    25. XM_017312714.3XP_017168203.1  transcriptional repressor p66 alpha isoform X1

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:420452
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    26. XM_030243466.2XP_030099326.1  transcriptional repressor p66 alpha isoform X6

      UniProtKB/Swiss-Prot
      Q8BTQ2, Q8CHY6, Q8VEC9
      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:416448
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    27. XM_036153937.1XP_036009830.1  transcriptional repressor p66 alpha isoform X5

      UniProtKB/TrEMBL
      A0A1I7Q4G8, E9QMN5
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:417450
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    28. XM_030243462.2XP_030099322.1  transcriptional repressor p66 alpha isoform X2

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:419452
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    29. XM_017312715.3XP_017168204.1  transcriptional repressor p66 alpha isoform X1

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:420452
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    30. XM_030243464.2XP_030099324.1  transcriptional repressor p66 alpha isoform X5

      UniProtKB/TrEMBL
      A0A1I7Q4G8, E9QMN5
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:417450
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    31. XM_036153934.1XP_036009827.1  transcriptional repressor p66 alpha isoform X2

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:419452
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    32. XM_017312717.3XP_017168206.1  transcriptional repressor p66 alpha isoform X1

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:420452
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    33. XM_036153935.1XP_036009828.1  transcriptional repressor p66 alpha isoform X5

      UniProtKB/TrEMBL
      A0A1I7Q4G8, E9QMN5
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:417450
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    34. XM_030243467.2XP_030099327.1  transcriptional repressor p66 alpha isoform X6

      UniProtKB/Swiss-Prot
      Q8BTQ2, Q8CHY6, Q8VEC9
      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:416448
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    35. XM_030243465.2XP_030099325.1  transcriptional repressor p66 alpha isoform X6

      UniProtKB/Swiss-Prot
      Q8BTQ2, Q8CHY6, Q8VEC9
      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:416448
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    36. XM_030243460.2XP_030099320.1  transcriptional repressor p66 alpha isoform X1

      UniProtKB/TrEMBL
      A0A1I7Q4G8
      Conserved Domains (2) summary
      pfam16563
      Location:133169
      P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
      cl29608
      Location:420452
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001113345.1: Suppressed sequence

      Description
      NM_001113345.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.