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    Mef2c myocyte enhancer factor 2C [ Mus musculus (house mouse) ]

    Gene ID: 17260, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mef2cprovided by MGI
    Official Full Name
    myocyte enhancer factor 2Cprovided by MGI
    Primary source
    MGI:MGI:99458
    See related
    Ensembl:ENSMUSG00000005583 AllianceGenome:MGI:99458
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mef2; 5430401D19Rik; 9930028G15Rik
    Summary
    Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; HMG box domain binding activity; and histone deacetylase binding activity. Involved in several processes, including heart development; modulation of chemical synaptic transmission; and positive regulation of cell differentiation. Acts upstream of with a negative effect on AMPA selective glutamate receptor signaling pathway and NMDA selective glutamate receptor signaling pathway. Acts upstream of or within several processes, including cardiac muscle hypertrophy in response to stress; circulatory system development; and skeletal system development. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; heart and pericardium; limb; and urinary system. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language. Orthologous to human MEF2C (myocyte enhancer factor 2C). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cortex adult (RPKM 49.3), frontal lobe adult (RPKM 37.4) and 11 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Mef2c in Genome Data Viewer
    Location:
    13 C3; 13 43.68 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (83652136..83815197)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (83504017..83667079)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_35149 Neighboring gene predicted gene, 33217 Neighboring gene predicted gene, 33274 Neighboring gene STARR-positive B cell enhancer ABC_E5408 Neighboring gene STARR-positive B cell enhancer mm9_chr13:83664236-83664536 Neighboring gene STARR-positive B cell enhancer mm9_chr13:83666025-83666326 Neighboring gene STARR-positive B cell enhancer mm9_chr13:83678903-83679204 Neighboring gene STARR-positive B cell enhancer ABC_E8895 Neighboring gene VISTA enhancer mm1175 Neighboring gene STARR-positive B cell enhancer ABC_E747 Neighboring gene predicted gene, 26803 Neighboring gene STARR-positive B cell enhancer mm9_chr13:83788426-83788726 Neighboring gene STARR-positive B cell enhancer mm9_chr13:83789544-83789845 Neighboring gene STARR-positive B cell enhancer mm9_chr13:83790286-83790587 Neighboring gene STARR-positive B cell enhancer ABC_E10805 Neighboring gene STARR-seq mESC enhancer starr_35152 Neighboring gene STARR-seq mESC enhancer starr_35153 Neighboring gene Mir9-2 host gene Neighboring gene microRNA 9b-2 Neighboring gene microRNA 9-2 Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables DNA-binding transcription activator activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA-binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables DNA-binding transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables HMG box domain binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables RNA polymerase II-specific DNA-binding transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables histone deacetylase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables histone deacetylase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables minor groove of adenine-thymine-rich DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription cis-regulatory region binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_negative_effect AMPA selective glutamate receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in B cell homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in B cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in B cell receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in MAPK cascade IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in MAPK cascade IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in MAPK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_negative_effect NMDA selective glutamate receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within blood vessel development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within blood vessel remodeling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within cardiac muscle cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in cardiac muscle cell differentiation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within cardiac muscle hypertrophy in response to stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within cardiac ventricle formation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in cardiac ventricle formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within cartilage morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within cell fate commitment IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cell morphogenesis involved in neuron differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of cell proliferation in bone marrow IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in cellular response to calcium ion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cellular response to fluid shear stress IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cellular response to growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to lipopolysaccharide IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cellular response to parathyroid hormone stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to parathyroid hormone stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cellular response to retinoic acid ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to transforming growth factor beta stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to transforming growth factor beta stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cellular response to trichostatin A IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cellular response to xenobiotic stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within chondrocyte differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in embryonic heart tube development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in embryonic heart tube development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within embryonic skeletal system morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within embryonic viscerocranium morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within endochondral ossification IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within endochondral ossification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in epithelial cell proliferation involved in renal tubule morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in excitatory postsynaptic potential IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in germinal center formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in glomerulus morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in heart development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within heart development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in heart looping IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in humoral immune response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in learning or memory IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in melanocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within monocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within muscle cell fate determination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of blood vessel endothelial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of epithelial cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of neuron apoptotic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of neuron apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of ossification ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of ossification ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of vascular associated smooth muscle cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of vascular associated smooth muscle cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of vascular endothelial cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nephron tubule epithelial cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neural crest cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuron development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuron differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuron migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in osteoblast differentiation IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    acts_upstream_of_or_within osteoblast differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within outflow tract morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in platelet formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of B cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of MAPK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of MAPK cascade ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of alkaline phosphatase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of behavioral fear response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of bone mineralization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of cardiac muscle cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of cardiac muscle cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cardiac muscle cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of cardiac muscle hypertrophy ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of cell proliferation in bone marrow IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of gene expression IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of macrophage apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of myoblast differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of myoblast differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of neuron differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of osteoblast differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of skeletal muscle cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of skeletal muscle tissue development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of skeletal muscle tissue development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in primary heart field specification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of dendritic spine development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of germinal center formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of megakaryocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of neuron apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of neurotransmitter secretion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of sarcomere organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of synapse assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of synaptic activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of synaptic plasticity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of synaptic transmission, glutamatergic IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in renal tubule morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in response to ischemia ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to ischemia ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within roof of mouth development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in secondary heart field specification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in semaphorin-plexin signaling pathway involved in axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sinoatrial valve morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within skeletal muscle cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in skeletal muscle cell differentiation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within skeletal muscle tissue development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within smooth muscle cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sympathetic neuron axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in transdifferentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ventricular cardiac muscle cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus IC
    Inferred by Curator
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in postsynapse IEA
    Inferred from Electronic Annotation
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in sarcomere ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sarcoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    myocyte-specific enhancer factor 2C

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001170537.2NP_001164008.1  myocyte-specific enhancer factor 2C isoform 1

      See identical proteins and their annotated locations for NP_001164008.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) lacks an alternate in-frame exon in the central coding region, compared to variant 3, resulting in an isoform (1) that is shorter than isoform 3.
      Source sequence(s)
      AC107750, CT025631, CU074400
      Consensus CDS
      CCDS49320.1
      UniProtKB/TrEMBL
      A0A0G2JDT0, Q3V1B5
      Related
      ENSMUSP00000143315.2, ENSMUST00000199450.5
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    2. NM_001347564.2NP_001334493.1  myocyte-specific enhancer factor 2C isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3). Variants 3, 4 and 5 all encode isoform 3.
      Source sequence(s)
      AC107750, CT025631, CU074400
      Consensus CDS
      CCDS84042.1
      UniProtKB/Swiss-Prot
      Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
      UniProtKB/TrEMBL
      A0A0G2JDT0
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    3. NM_001347566.2NP_001334495.1  myocyte-specific enhancer factor 2C isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 3. Variants 3, 4 and 5 all encode isoform 3.
      Source sequence(s)
      CT025631, CU074400
      Consensus CDS
      CCDS84042.1
      UniProtKB/Swiss-Prot
      Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
      UniProtKB/TrEMBL
      A0A0G2JDT0
      Related
      ENSMUSP00000143401.2, ENSMUST00000199019.5
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    4. NM_001347567.2NP_001334496.1  myocyte-specific enhancer factor 2C isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 3. Variants 3, 4 and 5 all encode isoform 3.
      Source sequence(s)
      CT025631, CU074400
      Consensus CDS
      CCDS84042.1
      UniProtKB/Swiss-Prot
      Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
      UniProtKB/TrEMBL
      A0A0G2JDT0
      Related
      ENSMUSP00000143212.2, ENSMUST00000199105.5
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    5. NM_001347568.2NP_001334497.1  myocyte-specific enhancer factor 2C isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR and uses an alternate in-frame exon in the 5' coding region, compared to variant 3. The encoded isoform (4) is shorter than isoform 3. Both variants 6 and 7 encode isoform 4.
      Source sequence(s)
      CT025631, CU074400
      Consensus CDS
      CCDS84045.1
      UniProtKB/TrEMBL
      A0A0G2JDT0
      Conserved Domains (2) summary
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:96150
      HJURP_C; Holliday junction regulator protein family C-terminal repeat
    6. NM_001347569.2NP_001334498.1  myocyte-specific enhancer factor 2C isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR and uses an alternate in-frame exon in the 5' coding region, compared to variant 3. The encoded isoform (4) is shorter than isoform 3. Both variants 6 and 7 encode isoform 4.
      Source sequence(s)
      CT025631, CU074400
      Consensus CDS
      CCDS84045.1
      UniProtKB/TrEMBL
      A0A0G2JDT0
      Related
      ENSMUSP00000138826.3, ENSMUST00000185052.6
      Conserved Domains (2) summary
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:96150
      HJURP_C; Holliday junction regulator protein family C-terminal repeat
    7. NM_001347571.2NP_001334500.1  myocyte-specific enhancer factor 2C isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.
      Source sequence(s)
      AC107750, CT025631, CU074400
      Consensus CDS
      CCDS84043.1
      UniProtKB/TrEMBL
      A0A0G2JE18
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    8. NM_001347572.2NP_001334501.1  myocyte-specific enhancer factor 2C isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.
      Source sequence(s)
      AC107750, CT025631, CU074400
      Consensus CDS
      CCDS84043.1
      UniProtKB/TrEMBL
      A0A0G2JE18
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    9. NM_001347573.2NP_001334502.1  myocyte-specific enhancer factor 2C isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.
      Source sequence(s)
      AC107750, CT025631, CU074400
      Consensus CDS
      CCDS84043.1
      UniProtKB/TrEMBL
      A0A0G2JE18
      Related
      ENSMUSP00000142595.2, ENSMUST00000199210.5
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    10. NM_001347574.2NP_001334503.1  myocyte-specific enhancer factor 2C isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.
      Source sequence(s)
      AC107750, CT025631, CU074400
      Consensus CDS
      CCDS84043.1
      UniProtKB/TrEMBL
      A0A0G2JE18
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    11. NM_001347575.2NP_001334504.1  myocyte-specific enhancer factor 2C isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (12) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.
      Source sequence(s)
      CT025631, CU074400
      Consensus CDS
      CCDS84043.1
      UniProtKB/TrEMBL
      A0A0G2JE18
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    12. NM_001347576.2NP_001334505.1  myocyte-specific enhancer factor 2C isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (13) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.
      Source sequence(s)
      CT025631, CU074400
      Consensus CDS
      CCDS84043.1
      UniProtKB/TrEMBL
      A0A0G2JE18
      Related
      ENSMUSP00000143420.2, ENSMUST00000197681.5
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    13. NM_001347577.2NP_001334506.1  myocyte-specific enhancer factor 2C isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (14) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.
      Source sequence(s)
      CT025631, CU074400
      Consensus CDS
      CCDS84043.1
      UniProtKB/TrEMBL
      A0A0G2JE18
      Related
      ENSMUSP00000143227.2, ENSMUST00000197146.5
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    14. NM_001347578.2NP_001334507.1  myocyte-specific enhancer factor 2C isoform 6

      Status: VALIDATED

      Description
      Transcript Variant: This variant (15) differs in the 5' UTR, lacks an in-frame exon in the central coding region, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3. The encoded isoform (6) is shorter than isoform 3.
      Source sequence(s)
      CT025631, CU074400
      Consensus CDS
      CCDS84044.1
      UniProtKB/TrEMBL
      A0A0G2JE18, A0A0G2JEC2
      Related
      ENSMUSP00000142714.2, ENSMUST00000199432.5
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    15. NM_001347579.2NP_001334508.1  myocyte-specific enhancer factor 2C isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (16) differs in the 5' UTR, and uses an alternate splice site that results in a frameshift in the 3' coding region, compared to variant 3. The encoded isoform (7) has a distinct C-terminus and is shorter than isoform 3. Both variants 16 and 17 encode isoform 7.
      Source sequence(s)
      AC107750, CT025631, CU074400
      UniProtKB/TrEMBL
      A0A0G2JDQ1
    16. NM_001347580.2NP_001334509.1  myocyte-specific enhancer factor 2C isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (17) differs in the 5' UTR, and uses an alternate splice site that results in a frameshift in the 3' coding region, compared to variant 3. The encoded isoform (7) has a distinct C-terminus and is shorter than isoform 3. Both variants 16 and 17 encode isoform 7.
      Source sequence(s)
      CT025631, CU074400
      UniProtKB/TrEMBL
      A0A0G2JDQ1
      Related
      ENSMUSP00000142456.2, ENSMUST00000197722.5
    17. NM_001347581.2NP_001334510.1  myocyte-specific enhancer factor 2C isoform 8

      Status: VALIDATED

      Description
      Transcript Variant: This variant (18) differs in the 5' UTR, lacks an in-frame exon in the central coding region, and uses an alternate splice site that results in a frameshift in the 3' coding region, compared to variant 3. The encoded isoform (8) has a distinct C-terminus and is shorter than isoform 3.
      Source sequence(s)
      CT025631, CU074400
      UniProtKB/TrEMBL
      A0A0G2JDQ1
    18. NM_025282.4NP_079558.1  myocyte-specific enhancer factor 2C isoform 2

      See identical proteins and their annotated locations for NP_079558.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate in-frame exon in the 5' coding region, lacks an in-frame exon in the central coding region, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3. The encoded isoform (2) is shorter than isoform 3.
      Source sequence(s)
      AC107750, CT025631, CU074400
      Consensus CDS
      CCDS26664.1
      UniProtKB/TrEMBL
      A0A0G2JE18
      Related
      ENSMUSP00000143742.2, ENSMUST00000198199.5
      Conserved Domains (2) summary
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:96150
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      83652136..83815197
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006517123.4XP_006517186.1  myocyte-specific enhancer factor 2C isoform X1

      See identical proteins and their annotated locations for XP_006517186.1

      UniProtKB/Swiss-Prot
      Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
      UniProtKB/TrEMBL
      A0A0G2JDT0
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    2. XM_036157888.1XP_036013781.1  myocyte-specific enhancer factor 2C isoform X4

      UniProtKB/TrEMBL
      A0A0G2JDT0, A0A0H2UKB6
      Related
      ENSMUSP00000005722.9, ENSMUST00000005722.14
      Conserved Domains (2) summary
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:96150
      HJURP_C; Holliday junction regulator protein family C-terminal repeat
    3. XM_036157891.1XP_036013784.1  myocyte-specific enhancer factor 2C isoform X6

      UniProtKB/TrEMBL
      A0A0G2JE18, A0A0G2JEC2
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    4. XM_036157892.1XP_036013785.1  myocyte-specific enhancer factor 2C isoform X6

      UniProtKB/TrEMBL
      A0A0G2JE18, A0A0G2JEC2
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    5. XM_030247172.2XP_030103032.1  myocyte-specific enhancer factor 2C isoform X1

      UniProtKB/Swiss-Prot
      Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
      UniProtKB/TrEMBL
      A0A0G2JDT0
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    6. XM_036157887.1XP_036013780.1  myocyte-specific enhancer factor 2C isoform X2

      UniProtKB/TrEMBL
      A0A0G2JDT0
      Conserved Domains (2) summary
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:96150
      HJURP_C; Holliday junction regulator protein family C-terminal repeat
    7. XM_017315405.3XP_017170894.1  myocyte-specific enhancer factor 2C isoform X1

      UniProtKB/Swiss-Prot
      Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
      UniProtKB/TrEMBL
      A0A0G2JDT0
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    8. XM_036157895.1XP_036013788.1  myocyte-specific enhancer factor 2C isoform X6

      UniProtKB/TrEMBL
      A0A0G2JE18, A0A0G2JEC2
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    9. XM_030247175.2XP_030103035.1  myocyte-specific enhancer factor 2C isoform X3

      UniProtKB/TrEMBL
      A0A0G2JDT0, Q3V1B5
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    10. XM_011244492.4XP_011242794.1  myocyte-specific enhancer factor 2C isoform X1

      See identical proteins and their annotated locations for XP_011242794.1

      UniProtKB/Swiss-Prot
      Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
      UniProtKB/TrEMBL
      A0A0G2JDT0
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    11. XM_030247177.2XP_030103037.1  myocyte-specific enhancer factor 2C isoform X8

      UniProtKB/TrEMBL
      A0A0G2JE18
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    12. XM_030247176.2XP_030103036.1  myocyte-specific enhancer factor 2C isoform X3

      UniProtKB/TrEMBL
      A0A0G2JDT0, Q3V1B5
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    13. XM_006517127.5XP_006517190.1  myocyte-specific enhancer factor 2C isoform X3

      See identical proteins and their annotated locations for XP_006517190.1

      UniProtKB/TrEMBL
      A0A0G2JDT0, Q3V1B5
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    14. XM_011244495.4XP_011242797.1  myocyte-specific enhancer factor 2C isoform X9

      UniProtKB/TrEMBL
      A0A0G2JDT0, A0A0H2UH28
      Related
      ENSMUSP00000132547.3, ENSMUST00000163888.8
      Conserved Domains (2) summary
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:116170
      HJURP_C; Holliday junction regulator protein family C-terminal repeat
    15. XM_006517126.4XP_006517189.1  myocyte-specific enhancer factor 2C isoform X2

      See identical proteins and their annotated locations for XP_006517189.1

      UniProtKB/TrEMBL
      A0A0G2JDT0
      Conserved Domains (2) summary
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:96150
      HJURP_C; Holliday junction regulator protein family C-terminal repeat
    16. XM_036157889.1XP_036013782.1  myocyte-specific enhancer factor 2C isoform X5

      UniProtKB/TrEMBL
      A0A0G2JE18
      Conserved Domains (2) summary
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:96150
      HJURP_C; Holliday junction regulator protein family C-terminal repeat
    17. XM_006517128.5XP_006517191.1  myocyte-specific enhancer factor 2C isoform X4

      UniProtKB/TrEMBL
      A0A0G2JDT0, A0A0H2UKB6
      Related
      ENSMUSP00000142487.2, ENSMUST00000198217.5
      Conserved Domains (2) summary
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:96150
      HJURP_C; Holliday junction regulator protein family C-terminal repeat
    18. XM_006517130.4XP_006517193.1  myocyte-specific enhancer factor 2C isoform X6

      See identical proteins and their annotated locations for XP_006517193.1

      UniProtKB/TrEMBL
      A0A0G2JE18, A0A0G2JEC2
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    19. XM_006517132.5XP_006517195.1  myocyte-specific enhancer factor 2C isoform X7

      See identical proteins and their annotated locations for XP_006517195.1

      UniProtKB/TrEMBL
      A0A0G2JE18
      Conserved Domains (2) summary
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:96150
      HJURP_C; Holliday junction regulator protein family C-terminal repeat
    20. XM_006517124.5XP_006517187.1  myocyte-specific enhancer factor 2C isoform X1

      See identical proteins and their annotated locations for XP_006517187.1

      UniProtKB/Swiss-Prot
      Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
      UniProtKB/TrEMBL
      A0A0G2JDT0
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    21. XM_036157893.1XP_036013786.1  myocyte-specific enhancer factor 2C isoform X6

      UniProtKB/TrEMBL
      A0A0G2JE18, A0A0G2JEC2
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    22. XM_036157890.1XP_036013783.1  myocyte-specific enhancer factor 2C isoform X8

      UniProtKB/TrEMBL
      A0A0G2JE18
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    23. XM_036157894.1XP_036013787.1  myocyte-specific enhancer factor 2C isoform X6

      UniProtKB/TrEMBL
      A0A0G2JE18, A0A0G2JEC2
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    24. XM_036157886.1XP_036013779.1  myocyte-specific enhancer factor 2C isoform X1

      UniProtKB/Swiss-Prot
      Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
      UniProtKB/TrEMBL
      A0A0G2JDT0
      Conserved Domains (2) summary
      COG5068
      Location:1245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:278
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...