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    Chpf2 chondroitin polymerizing factor 2 [ Mus musculus (house mouse) ]

    Gene ID: 100910, updated on 9-Dec-2024

    Summary

    Official Symbol
    Chpf2provided by MGI
    Official Full Name
    chondroitin polymerizing factor 2provided by MGI
    Primary source
    MGI:MGI:1917522
    See related
    Ensembl:ENSMUSG00000038181 AllianceGenome:MGI:1917522
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm42230; mir-671; mKIAA1402; 2010209O12Rik
    Summary
    Predicted to enable N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity and glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process. Is active in Golgi apparatus. Is expressed in articular cartilage; cartilage; and humerus. Orthologous to human CHPF2 (chondroitin polymerizing factor 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in genital fat pad adult (RPKM 27.5), ovary adult (RPKM 21.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Chpf2 in Genome Data Viewer
    Location:
    5; 5 A3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (24788950..24799396)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (24586744..24594398)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E6314 Neighboring gene ATP-binding cassette, sub-family F member 2 Neighboring gene ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g pseudogene Neighboring gene SWI/SNF related BAF chromatin remodeling complex subunit D3 Neighboring gene microRNA 671 Neighboring gene glycerol-3-phosphate dehydrogenase 1-like pseudogene Neighboring gene STARR-seq mESC enhancer starr_12645 Neighboring gene STARR-positive B cell enhancer mm9_chr5:24180078-24180378 Neighboring gene STARR-positive B cell enhancer ABC_E1298 Neighboring gene STARR-positive B cell enhancer ABC_E11722 Neighboring gene negative regulator of ubiquitin-like proteins 1 Neighboring gene WD repeat domain 86

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1)  1 citation

    General protein information

    Preferred Names
    chondroitin sulfate glucuronyltransferase
    NP_598674.2
    XP_036020598.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133913.2NP_598674.2  chondroitin sulfate glucuronyltransferase precursor

      See identical proteins and their annotated locations for NP_598674.2

      Status: VALIDATED

      Source sequence(s)
      AK122504, BC036970
      Consensus CDS
      CCDS51436.1
      UniProtKB/TrEMBL
      Q3UU43, Q80TE1
      Related
      ENSMUSP00000112804.2, ENSMUST00000121863.5
      Conserved Domains (2) summary
      pfam05679
      Location:242755
      CHGN; Chondroitin N-acetylgalactosaminyltransferase
      cl21608
      Location:177269
      Galactosyl_T; Galactosyltransferase

    RNA

    1. NR_155297.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC116136, AK138814, BE854619

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      24788950..24799396
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036164705.1XP_036020598.1  chondroitin sulfate glucuronyltransferase isoform X1

      UniProtKB/TrEMBL
      Q3UU43, Q80TE1
      Related
      ENSMUSP00000085633.5, ENSMUST00000088295.9
      Conserved Domains (2) summary
      pfam05679
      Location:242755
      CHGN; Chondroitin N-acetylgalactosaminyltransferase
      cl21608
      Location:177269
      Galactosyl_T; Galactosyltransferase