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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_028005.1 RefSeqGene
- Range
-
5001..69722
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001024937.4 → NP_001020108.1 misshapen-like kinase 1 isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an alternate in-frame exon and contains another alternate in-frame exon compared to variant 1. The resulting isoform (4) has the same N- and C-termini and is longer compared to isoform 1.
- Source sequence(s)
-
AB041926, AL157418, AY775058, DA653105
- Consensus CDS
-
CCDS45590.1
- UniProtKB/Swiss-Prot
-
Q8N4C8
- Related
- ENSP00000406487.3, ENST00000453408.7
- Conserved Domains (3) summary
-
- smart00036
Location:994 → 1292
- CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
- smart00220
Location:25 → 289
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd06636
Location:8 → 289
- STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6
-
NM_001321236.2 → NP_001308165.1 misshapen-like kinase 1 isoform 5
Status: REVIEWED
- Source sequence(s)
-
AB041926, AL157418, BC094686, DA653105
- UniProtKB/Swiss-Prot
-
Q8N4C8
- Conserved Domains (3) summary
-
- smart00036
Location:922 → 1220
- CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
- smart00220
Location:11 → 234
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cl21453
Location:1 → 234
- PKc_like; Protein Kinases, catalytic domain
-
NM_015716.5 → NP_056531.1 misshapen-like kinase 1 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the shortest transcript and encodes the shortest isoform (1).
- Source sequence(s)
-
AB035698, AB041926, AL157418, DA653105
- UniProtKB/Swiss-Prot
-
Q8N4C8
- Conserved Domains (3) summary
-
- smart00036
Location:977 → 1275
- CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
- smart00220
Location:25 → 289
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd06636
Location:8 → 289
- STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6
-
NM_153827.5 → NP_722549.2 misshapen-like kinase 1 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) includes an additional in-frame exon, compared to variant 1, resulting in the longest isoform (3) which has a unique internal segment, compared to isoform 1.
- Source sequence(s)
-
AB035698, AB041926, AL157418, BC034673, DA653105
- Consensus CDS
-
CCDS45588.1
- UniProtKB/Swiss-Prot
- D3DTK3, D3DTK4, Q5U8Z0, Q8N4C8, Q9P1X1, Q9P2R8
- Related
- ENSP00000347427.6, ENST00000355280.11
- Conserved Domains (3) summary
-
- smart00036
Location:1014 → 1312
- CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
- smart00220
Location:25 → 289
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd06636
Location:8 → 289
- STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6
-
NM_170663.5 → NP_733763.1 misshapen-like kinase 1 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) includes an additional in-frame exon, compared to variant 1, resulting in a longer isoform (2) that has a unique internal segment, compared to isoform 1.
- Source sequence(s)
-
AB041926, AL157418, DA653105
- Consensus CDS
-
CCDS45589.1
- UniProtKB/Swiss-Prot
-
Q8N4C8
- Related
- ENSP00000269296.7, ENST00000347992.11
- Conserved Domains (3) summary
-
- smart00036
Location:985 → 1283
- CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
- smart00220
Location:25 → 289
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd06636
Location:8 → 289
- STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000017.11 Reference GRCh38.p14 Primary Assembly
- Range
-
4833340..4898061
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_006721531.2 → XP_006721594.1 misshapen-like kinase 1 isoform X1
- Conserved Domains (3) summary
-
- smart00036
Location:1043 → 1341
- CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
- smart00220
Location:25 → 289
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd06636
Location:8 → 289
- STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6
-
XM_006721532.2 → XP_006721595.1 misshapen-like kinase 1 isoform X2
- Conserved Domains (3) summary
-
- smart00036
Location:1042 → 1340
- CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
- smart00220
Location:25 → 289
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd06636
Location:8 → 289
- STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6
-
XM_006721536.2 → XP_006721599.1 misshapen-like kinase 1 isoform X11
- Conserved Domains (3) summary
-
- smart00036
Location:1006 → 1304
- CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
- smart00220
Location:25 → 289
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd06636
Location:8 → 289
- STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6
-
XM_017024706.1 → XP_016880195.1 misshapen-like kinase 1 isoform X12
-
XM_017024705.1 → XP_016880194.1 misshapen-like kinase 1 isoform X5
-
XM_047436166.1 → XP_047292122.1 misshapen-like kinase 1 isoform X6
-
XM_047436168.1 → XP_047292124.1 misshapen-like kinase 1 isoform X8
-
XM_047436173.1 → XP_047292129.1 misshapen-like kinase 1 isoform X17
-
XM_047436170.1 → XP_047292126.1 misshapen-like kinase 1 isoform X13
-
XM_047436176.1 → XP_047292132.1 misshapen-like kinase 1 isoform X21
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XM_047436177.1 → XP_047292133.1 misshapen-like kinase 1 isoform X22
-
XM_017024704.1 → XP_016880193.1 misshapen-like kinase 1 isoform X3
-
XM_047436165.1 → XP_047292121.1 misshapen-like kinase 1 isoform X4
-
XM_047436167.1 → XP_047292123.1 misshapen-like kinase 1 isoform X7
-
XM_011523906.1 → XP_011522208.1 misshapen-like kinase 1 isoform X9
- Conserved Domains (3) summary
-
- smart00036
Location:1011 → 1309
- CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
- smart00220
Location:25 → 289
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd06636
Location:8 → 289
- STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6
-
XM_047436169.1 → XP_047292125.1 misshapen-like kinase 1 isoform X10
-
XM_047436174.1 → XP_047292130.1 misshapen-like kinase 1 isoform X18
-
XM_047436175.1 → XP_047292131.1 misshapen-like kinase 1 isoform X19
-
XM_047436171.1 → XP_047292127.1 misshapen-like kinase 1 isoform X14
-
XM_047436172.1 → XP_047292128.1 misshapen-like kinase 1 isoform X15
-
XM_047436178.1 → XP_047292134.1 misshapen-like kinase 1 isoform X23
- Related
-
ENST00000572330.5
-
XM_047436179.1 → XP_047292135.1 misshapen-like kinase 1 isoform X24
-
XM_017024708.2 → XP_016880197.1 misshapen-like kinase 1 isoform X20
-
XM_017024707.3 → XP_016880196.1 misshapen-like kinase 1 isoform X16
Alternate T2T-CHM13v2.0
Genomic
-
NC_060941.1 Alternate T2T-CHM13v2.0
- Range
-
4722898..4788313
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054316305.1 → XP_054172280.1 misshapen-like kinase 1 isoform X1
-
XM_054316306.1 → XP_054172281.1 misshapen-like kinase 1 isoform X2
-
XM_054316315.1 → XP_054172290.1 misshapen-like kinase 1 isoform X11
-
XM_054316316.1 → XP_054172291.1 misshapen-like kinase 1 isoform X12
-
XM_054316309.1 → XP_054172284.1 misshapen-like kinase 1 isoform X5
-
XM_054316310.1 → XP_054172285.1 misshapen-like kinase 1 isoform X6
-
XM_054316312.1 → XP_054172287.1 misshapen-like kinase 1 isoform X8
-
XM_054316321.1 → XP_054172296.1 misshapen-like kinase 1 isoform X17
-
XM_054316317.1 → XP_054172292.1 misshapen-like kinase 1 isoform X13
-
XM_054316325.1 → XP_054172300.1 misshapen-like kinase 1 isoform X21
-
XM_054316326.1 → XP_054172301.1 misshapen-like kinase 1 isoform X22
-
XM_054316307.1 → XP_054172282.1 misshapen-like kinase 1 isoform X3
-
XM_054316308.1 → XP_054172283.1 misshapen-like kinase 1 isoform X4
-
XM_054316311.1 → XP_054172286.1 misshapen-like kinase 1 isoform X7
-
XM_054316313.1 → XP_054172288.1 misshapen-like kinase 1 isoform X9
-
XM_054316314.1 → XP_054172289.1 misshapen-like kinase 1 isoform X10
-
XM_054316322.1 → XP_054172297.1 misshapen-like kinase 1 isoform X18
-
XM_054316323.1 → XP_054172298.1 misshapen-like kinase 1 isoform X19
-
XM_054316318.1 → XP_054172293.1 misshapen-like kinase 1 isoform X14
-
XM_054316319.1 → XP_054172294.1 misshapen-like kinase 1 isoform X15
-
XM_054316327.1 → XP_054172302.1 misshapen-like kinase 1 isoform X23
-
XM_054316328.1 → XP_054172303.1 misshapen-like kinase 1 isoform X24
-
XM_054316320.1 → XP_054172295.1 misshapen-like kinase 1 isoform X16
-
XM_054316324.1 → XP_054172299.1 misshapen-like kinase 1 isoform X20