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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001134335.2 → NP_001127807.1 eukaryotic translation initiation factor 2-alpha kinase 1 isoform b
See identical proteins and their annotated locations for NP_001127807.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate in-frame splice site at the end of an exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is 1 aa shorter compared to isoform a.
- Source sequence(s)
-
AC005995, AL136563, DC341983
- UniProtKB/Swiss-Prot
-
Q9BQI3
- Conserved Domains (2) summary
-
- smart00220
Location:167 → 582
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd14049
Location:160 → 580
- STKc_EIF2AK1_HRI; Catalytic domain of the Serine/Threonine kinase, eukaryotic translation Initiation Factor 2-Alpha Kinase 2 or Heme-Regulated Inhibitor kinase
-
NM_014413.4 → NP_055228.2 eukaryotic translation initiation factor 2-alpha kinase 1 isoform a
See identical proteins and their annotated locations for NP_055228.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
- Source sequence(s)
-
AC005995, BC006524, DC341983
- Consensus CDS
-
CCDS5345.1
- UniProtKB/Swiss-Prot
- A8K2R2, Q549K6, Q8NBW3, Q9BQI3, Q9HC02, Q9NYE0, Q9P0V6, Q9P1J5, Q9P2H8, Q9UHG4
- Related
- ENSP00000199389.6, ENST00000199389.11
- Conserved Domains (2) summary
-
- smart00220
Location:167 → 583
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd14049
Location:160 → 581
- STKc_EIF2AK1_HRI; Catalytic domain of the Serine/Threonine kinase, eukaryotic translation Initiation Factor 2-Alpha Kinase 2 or Heme-Regulated Inhibitor kinase
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000007.14 Reference GRCh38.p14 Primary Assembly
- Range
-
6022247..6059175 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047420200.1 → XP_047276156.1 eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1
- UniProtKB/TrEMBL
-
Q75MR0
Alternate T2T-CHM13v2.0
Genomic
-
NC_060931.1 Alternate T2T-CHM13v2.0
- Range
-
6140020..6176976 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054357905.1 → XP_054213880.1 eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1
- UniProtKB/TrEMBL
-
Q75MR0