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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_047118.2 RefSeqGene
- Range
-
5002..58620
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001014831.3 → NP_001014831.1 serine/threonine-protein kinase PAK 4 isoform 1
See identical proteins and their annotated locations for NP_001014831.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) has an additional segment in the 5' UTR, and encodes the same isoform (1), as compared to variant 1.
- Source sequence(s)
-
AB032968, AC011443, BC025282, BG773480
- Consensus CDS
-
CCDS12528.1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
- Related
- ENSP00000469413.1, ENST00000593690.5
- Conserved Domains (2) summary
-
- cd06657
Location:300 → 591
- STKc_PAK4; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 4
- cd01093
Location:10 → 55
- CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
-
NM_001014832.2 → NP_001014832.1 serine/threonine-protein kinase PAK 4 isoform 1
See identical proteins and their annotated locations for NP_001014832.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an exon in the 5' UTR, and encodes the same isoform (1), as compared to variant 1.
- Source sequence(s)
-
AB032968, AC011443, BC011368, BC025282, BG773480
- Consensus CDS
-
CCDS12528.1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
- Related
- ENSP00000351049.2, ENST00000358301.7
- Conserved Domains (2) summary
-
- cd06657
Location:300 → 591
- STKc_PAK4; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 4
- cd01093
Location:10 → 55
- CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
-
NM_001014834.3 → NP_001014834.1 serine/threonine-protein kinase PAK 4 isoform 2
See identical proteins and their annotated locations for NP_001014834.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks an exon in the 5' UTR and an in-frame exon in the coding region, as compared to variant 1. The encoded isoform (2) thus lacks an internal segment, as compared to isoform 1.
- Source sequence(s)
-
AB032968, AC011443, AL834236, BG773480
- Consensus CDS
-
CCDS33019.1
- UniProtKB/TrEMBL
-
B4DE88
- Related
- ENSP00000470284.1, ENST00000599470.5
- Conserved Domains (2) summary
-
- cd01093
Location:10 → 55
- CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
- cl21453
Location:147 → 438
- PKc_like; Protein Kinases, catalytic domain
-
NM_001014835.2 → NP_001014835.1 serine/threonine-protein kinase PAK 4 isoform 2
See identical proteins and their annotated locations for NP_001014835.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an in-frame exon in the coding region, as compared to variant 1. The encoded isoform (2) thus lacks an internal segment, as compared to isoform 1.
- Source sequence(s)
-
AB032968, AC011443, BG773480
- Consensus CDS
-
CCDS33019.1
- UniProtKB/TrEMBL
-
B4DE88
- Related
- ENSP00000471157.1, ENST00000599386.5
- Conserved Domains (2) summary
-
- cd01093
Location:10 → 55
- CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
- cl21453
Location:147 → 438
- PKc_like; Protein Kinases, catalytic domain
-
NM_001394501.1 → NP_001381430.1 serine/threonine-protein kinase PAK 4 isoform 1
Status: REVIEWED
- Source sequence(s)
-
AC011443
- Consensus CDS
-
CCDS12528.1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
- Conserved Domains (2) summary
-
- cd06657
Location:300 → 591
- STKc_PAK4; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 4
- cd01093
Location:10 → 55
- CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
-
NM_005884.5 → NP_005875.1 serine/threonine-protein kinase PAK 4 isoform 1
See identical proteins and their annotated locations for NP_005875.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
AB032968, AF005046, BG773480
- Consensus CDS
-
CCDS12528.1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
- Related
- ENSP00000353625.3, ENST00000360442.8
- Conserved Domains (2) summary
-
- cd06657
Location:300 → 591
- STKc_PAK4; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 4
- cd01093
Location:10 → 55
- CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000019.10 Reference GRCh38.p14 Primary Assembly
- Range
-
39125786..39182816
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011526316.2 → XP_011524618.1 serine/threonine-protein kinase PAK 4 isoform X1
See identical proteins and their annotated locations for XP_011524618.1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
- Conserved Domains (2) summary
-
- cd06657
Location:300 → 591
- STKc_PAK4; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 4
- cd01093
Location:10 → 55
- CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
-
XM_011526320.2 → XP_011524622.1 serine/threonine-protein kinase PAK 4 isoform X2
See identical proteins and their annotated locations for XP_011524622.1
- UniProtKB/TrEMBL
-
B4DE88
- Conserved Domains (2) summary
-
- cd01093
Location:10 → 55
- CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
- cl21453
Location:147 → 438
- PKc_like; Protein Kinases, catalytic domain
-
XM_047438034.1 → XP_047293990.1 serine/threonine-protein kinase PAK 4 isoform X1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
-
XM_024451314.2 → XP_024307082.1 serine/threonine-protein kinase PAK 4 isoform X2
- UniProtKB/TrEMBL
-
B4DE88
- Conserved Domains (2) summary
-
- cd01093
Location:10 → 55
- CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
- cl21453
Location:147 → 438
- PKc_like; Protein Kinases, catalytic domain
-
XM_011526317.3 → XP_011524619.1 serine/threonine-protein kinase PAK 4 isoform X1
See identical proteins and their annotated locations for XP_011524619.1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
- Conserved Domains (2) summary
-
- cd06657
Location:300 → 591
- STKc_PAK4; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 4
- cd01093
Location:10 → 55
- CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
-
XM_047438040.1 → XP_047293996.1 serine/threonine-protein kinase PAK 4 isoform X2
- UniProtKB/TrEMBL
-
B4DE88
-
XM_047438037.1 → XP_047293993.1 serine/threonine-protein kinase PAK 4 isoform X1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
-
XM_047438038.1 → XP_047293994.1 serine/threonine-protein kinase PAK 4 isoform X1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
-
XM_047438036.1 → XP_047293992.1 serine/threonine-protein kinase PAK 4 isoform X1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
-
XM_047438035.1 → XP_047293991.1 serine/threonine-protein kinase PAK 4 isoform X1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
-
XM_047438041.1 → XP_047293997.1 serine/threonine-protein kinase PAK 4 isoform X2
- UniProtKB/TrEMBL
-
B4DE88
Alternate T2T-CHM13v2.0
Genomic
-
NC_060943.1 Alternate T2T-CHM13v2.0
- Range
-
41929765..41986971
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054319503.1 → XP_054175478.1 serine/threonine-protein kinase PAK 4 isoform X1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
-
XM_054319510.1 → XP_054175485.1 serine/threonine-protein kinase PAK 4 isoform X2
- UniProtKB/TrEMBL
-
B4DE88
-
XM_054319504.1 → XP_054175479.1 serine/threonine-protein kinase PAK 4 isoform X1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
-
XM_054319505.1 → XP_054175480.1 serine/threonine-protein kinase PAK 4 isoform X1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
-
XM_054319512.1 → XP_054175487.1 serine/threonine-protein kinase PAK 4 isoform X2
- UniProtKB/TrEMBL
-
B4DE88
-
XM_054319511.1 → XP_054175486.1 serine/threonine-protein kinase PAK 4 isoform X2
- UniProtKB/TrEMBL
-
B4DE88
-
XM_054319508.1 → XP_054175483.1 serine/threonine-protein kinase PAK 4 isoform X1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
-
XM_054319509.1 → XP_054175484.1 serine/threonine-protein kinase PAK 4 isoform X1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
-
XM_054319507.1 → XP_054175482.1 serine/threonine-protein kinase PAK 4 isoform X1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
-
XM_054319506.1 → XP_054175481.1 serine/threonine-protein kinase PAK 4 isoform X1
- UniProtKB/Swiss-Prot
- B4DGG6, O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
- UniProtKB/TrEMBL
-
A8K724
-
XM_054319513.1 → XP_054175488.1 serine/threonine-protein kinase PAK 4 isoform X2
- UniProtKB/TrEMBL
-
B4DE88
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_001014833.1: Suppressed sequence
- Description
- NM_001014833.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.