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    CYP2T1P cytochrome P450 family 2 subfamily T member 1, pseudogene [ Homo sapiens (human) ]

    Gene ID: 171523, updated on 10-Dec-2024

    Summary

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    Official Symbol
    CYP2T1Pprovided by HGNC
    Official Full Name
    cytochrome P450 family 2 subfamily T member 1, pseudogeneprovided by HGNC
    Primary source
    HGNC:HGNC:18852
    See related
    Ensembl:ENSG00000293405 AllianceGenome:HGNC:18852
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CYP2T2P
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    Genomic context

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    See CYP2T1P in Genome Data Viewer
    Location:
    19q13.2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (40808443..40811100, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (43629122..43631779, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (41314348..41317005, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10648 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14667 Neighboring gene MIA-RAB4B readthrough (NMD candidate) Neighboring gene RAB4B-EGLN2 readthrough (NMD candidate) Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:41285223-41285754 Neighboring gene RAB4B, member RAS oncogene family Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10649 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10650 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:41306857-41307531 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:41307710-41308450 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14668 Neighboring gene egl-9 family hypoxia inducible factor 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:41314255-41314754 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:41317625-41318515 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14669 Neighboring gene cytochrome P450 family 2 subfamily F member 2, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:41332287-41332788 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:41332789-41333288 Neighboring gene Sharpr-MPRA regulatory region 4763 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:41354211-41354710 Neighboring gene cytochrome P450 family 2 subfamily A member 6 Neighboring gene CYP2A6 5' regulatory region

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Organization, structure and evolution of the CYP2 gene cluster on human chromosome 19. Hoffman SM, et al. Pharmacogenetics, 2001 Nov. PMID 11692077
    2. Organization and evolution of the Cyp2 gene cluster on mouse chromosome 7, and comparison with the syntenic human cluster. Wang H, et al. Environ Health Perspect, 2003 Nov. PMID 14630516, Free PMC Article
    3. Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates. Zhang ZD, et al. Genome Biol, 2010. PMID 20210993, Free PMC Article
    4. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. Nelson DR, et al. Pharmacogenetics, 2004 Jan. PMID 15128046
    5. SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity. Shi P, et al. J Immunol, 2020 Jul 1. PMID 32393512

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • cytochrome P450, family 2, subfamily F, polypeptide 1 pseudogene
    • cytochrome P450, family 2, subfamily T, polypeptide 1, pseudogene
    • cytochrome P450, family 2, subfamily T, polypeptide 2, pseudogene
    • cytochrome P450, subfamily IIT, polypeptide 2 pseudogene

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_144551.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008537, BX281617, DA593489
      Related
      ENST00000641596.2

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      40808443..40811100 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      43629122..43631779 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_024182.1: Suppressed sequence

      Description
      NG_024182.1: This RefSeq was permanently suppressed because it was redundant with the annotation of geneID:171523 on NG_000008.7

    2. NG_027794.1: Suppressed sequence

      Description
      NG_027794.1: This RefSeq was permanently suppressed because it was redundant with the annotation of geneID:171523 on NG_000008.7
    Nucleotide Protein
    Heading Accession and Version

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