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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_008768.1 RefSeqGene
- Range
-
5011..446353
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_000282.4 → NP_000273.2 propionyl-CoA carboxylase alpha chain, mitochondrial isoform a precursor
See identical proteins and their annotated locations for NP_000273.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (a).
- Source sequence(s)
-
AF385926, BC000140
- Consensus CDS
-
CCDS9496.2
- UniProtKB/Swiss-Prot
- B4DKY8, B4DPF9, C9JPQ8, P05165, Q15979, Q8WXQ7
- UniProtKB/TrEMBL
-
B2RDE0
- Related
- ENSP00000365462.1, ENST00000376285.6
- Conserved Domains (5) summary
-
- cd06850
Location:661 → 727
- biotinyl_domain; The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase, ...
- smart00878
Location:397 → 504
- Biotin_carb_C; Biotin carboxylase C-terminal domain
- COG4770
Location:63 → 728
- PccA; Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid transport and metabolism]
- pfam00289
Location:63 → 171
- CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain
- pfam02786
Location:176 → 383
- CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain
-
NM_001127692.3 → NP_001121164.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform b
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to NM_000282.3.
- Source sequence(s)
-
AF385926, BC000140, DA781564
- Consensus CDS
-
CCDS45065.1
- UniProtKB/TrEMBL
-
B2RDE0
- Related
- ENSP00000365463.4, ENST00000376286.8
- Conserved Domains (5) summary
-
- cd06850
Location:635 → 701
- biotinyl_domain; The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase, ...
- smart00878
Location:371 → 478
- Biotin_carb_C; Biotin carboxylase C-terminal domain
- COG4770
Location:37 → 702
- PccA; Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid transport and metabolism]
- pfam00289
Location:37 → 145
- CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain
- pfam02786
Location:150 → 357
- CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain
-
NM_001178004.2 → NP_001171475.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform c precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 3' coding region compared to variant 1. The resulting protein (isoform c) is shorter compared to isoform a.
- Source sequence(s)
-
AK298318, AL356575, CB851764
- Consensus CDS
-
CCDS53878.1
- UniProtKB/TrEMBL
-
B2RDE0
- Related
- ENSP00000365456.3, ENST00000376279.7
- Conserved Domains (5) summary
-
- cd06850
Location:631 → 680
- biotinyl_domain; The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase, ...
- smart00878
Location:397 → 504
- Biotin_carb_C; Biotin carboxylase C-terminal domain
- COG4770
Location:63 → 681
- PccA; Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid transport and metabolism]
- pfam00289
Location:63 → 171
- CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain
- pfam02786
Location:176 → 383
- CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain
-
NM_001352605.2 → NP_001339534.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform d precursor
Status: REVIEWED
- Source sequence(s)
-
AL136526, AL353697, AL355338, AL356575
- UniProtKB/TrEMBL
-
B2RDE0
- Conserved Domains (1) summary
-
- COG4770
Location:63 → 710
- PccA; Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid transport and metabolism]
-
NM_001352606.2 → NP_001339535.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform e precursor
Status: REVIEWED
- Source sequence(s)
-
AL136526, AL353697, AL355338, AL356575
- UniProtKB/TrEMBL
-
A0A1B0GU58
- Related
- ENSP00000489974.1, ENST00000637657.1
- Conserved Domains (1) summary
-
- cl27361
Location:63 → 680
- Biotin_carb_C; Biotin carboxylase C-terminal domain
-
NM_001352607.2 → NP_001339536.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform f
Status: REVIEWED
- Source sequence(s)
-
AL136526, AL353697, AL355338, AL356575
- UniProtKB/TrEMBL
-
B2RDE0
- Conserved Domains (1) summary
-
- cl27361
Location:37 → 655
- Biotin_carb_C; Biotin carboxylase C-terminal domain
-
NM_001352608.2 → NP_001339537.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform g
Status: REVIEWED
- Source sequence(s)
-
AL136526, AL353697, AL355338, AL356575
- UniProtKB/TrEMBL
-
A0A1B0GU58
- Conserved Domains (1) summary
-
- cl27361
Location:37 → 654
- Biotin_carb_C; Biotin carboxylase C-terminal domain
-
NM_001352609.2 → NP_001339538.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform h precursor
Status: REVIEWED
- Source sequence(s)
-
AL136526, AL353697, AL355338, AL356575
- UniProtKB/TrEMBL
-
B2RDE0
- Conserved Domains (1) summary
-
- cl27361
Location:63 → 592
- Biotin_carb_C; Biotin carboxylase C-terminal domain
-
NM_001352610.2 → NP_001339539.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform i
Status: REVIEWED
- Source sequence(s)
-
AL136526, AL353697, AL355338, AL356575
- Conserved Domains (1) summary
-
- cl27361
Location:1 → 413
- Biotin_carb_C; Biotin carboxylase C-terminal domain
-
NM_001352611.2 → NP_001339540.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform j
Status: REVIEWED
- Source sequence(s)
-
AL136526, AL353697, AL355338, AL356575
- Conserved Domains (1) summary
-
- cl27361
Location:1 → 395
- Biotin_carb_C; Biotin carboxylase C-terminal domain
-
NM_001352612.2 → NP_001339541.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform k
Status: REVIEWED
- Source sequence(s)
-
AL136526, AL353697, AL355338, AL356575
- Conserved Domains (1) summary
-
- cl27361
Location:1 → 365
- Biotin_carb_C; Biotin carboxylase C-terminal domain
RNA
-
NR_148027.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AL136526, AL353697, AL355338, AL356575
-
NR_148028.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AL136526, AL353697, AL355338, AL356575
-
NR_148029.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AL136526, AL353697, AL355338, AL356575
-
NR_148030.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AL136526, AL353697, AL355338, AL356575
-
NR_148031.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AL136526, AL353697, AL355338, AL356575
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000013.11 Reference GRCh38.p14 Primary Assembly
- Range
-
100089093..100530435
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017020609.2 → XP_016876098.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X5
- UniProtKB/TrEMBL
-
B2RDE0
- Conserved Domains (5) summary
-
- cd06850
Location:628 → 694
- biotinyl_domain; The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase, ...
- smart00878
Location:364 → 471
- Biotin_carb_C; Biotin carboxylase C-terminal domain
- COG4770
Location:30 → 695
- PccA; Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid transport and metabolism]
- pfam00289
Location:30 → 138
- CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain
- pfam02786
Location:143 → 350
- CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain
-
XM_047430373.1 → XP_047286329.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X12
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_017020613.2 → XP_016876102.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X11
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_047430371.1 → XP_047286327.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X7
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_017020612.2 → XP_016876101.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X9
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_017020611.2 → XP_016876100.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X8
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_011521093.2 → XP_011519395.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X4
- UniProtKB/TrEMBL
-
B2RDE0
- Conserved Domains (4) summary
-
- smart00878
Location:397 → 504
- Biotin_carb_C; Biotin carboxylase C-terminal domain
- PRK08591
Location:62 → 504
- PRK08591; acetyl-CoA carboxylase biotin carboxylase subunit; Validated
- pfam00289
Location:63 → 171
- CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain
- pfam02786
Location:176 → 383
- CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain
-
XM_047430372.1 → XP_047286328.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X10
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_047430375.1 → XP_047286331.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X15
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_017020607.2 → XP_016876096.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X3
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_017020605.2 → XP_016876094.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X1
-
XM_017020606.2 → XP_016876095.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X2
-
XM_047430374.1 → XP_047286330.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X13
-
XM_017020615.2 → XP_016876104.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X14
-
XM_017020616.2 → XP_016876105.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X16
-
XM_047430377.1 → XP_047286333.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X18
- UniProtKB/TrEMBL
-
A0A1B0GWA1
- Related
- ENSP00000490843.1, ENST00000636475.1
-
XM_047430370.1 → XP_047286326.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X6
-
XM_047430376.1 → XP_047286332.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X17
-
XM_047430378.1 → XP_047286334.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X19
RNA
-
XR_007063681.1 RNA Sequence
Alternate T2T-CHM13v2.0
Genomic
-
NC_060937.1 Alternate T2T-CHM13v2.0
- Range
-
99302579..99745721
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054374576.1 → XP_054230551.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X5
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_054374583.1 → XP_054230558.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X12
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_054374574.1 → XP_054230549.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X3
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_054374582.1 → XP_054230557.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X11
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_054374578.1 → XP_054230553.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X7
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_054374579.1 → XP_054230554.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X8
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_054374575.1 → XP_054230550.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X4
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_054374581.1 → XP_054230556.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X10
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_054374586.1 → XP_054230561.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X15
- UniProtKB/TrEMBL
-
B2RDE0
-
XM_054374572.1 → XP_054230547.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X1
-
XM_054374573.1 → XP_054230548.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X2
-
XM_054374584.1 → XP_054230559.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X13
-
XM_054374585.1 → XP_054230560.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X14
-
XM_054374587.1 → XP_054230562.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X16
-
XM_054374589.1 → XP_054230564.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X18
- UniProtKB/TrEMBL
-
A0A1B0GWA1
-
XM_054374577.1 → XP_054230552.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X6
-
XM_054374588.1 → XP_054230563.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X17
-
XM_054374590.1 → XP_054230565.1 propionyl-CoA carboxylase alpha chain, mitochondrial isoform X19
RNA
-
XR_008488765.1 RNA Sequence
-
XR_008488764.1 RNA Sequence
-
XR_008488763.1 RNA Sequence