NEW
Try the new Transcript table
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001377418.1 → NP_001364347.1 rho guanine nucleotide exchange factor 11 isoform 3
Status: REVIEWED
- Source sequence(s)
-
AL157713, AL356104
- UniProtKB/TrEMBL
-
A0AAQ5BII7
- Related
- ENSP00000520489.1, ENST00000715595.1
- Conserved Domains (5) summary
-
- cd08753
Location:326 → 470
- RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
- PHA03307
Location:1209 → 1559
- PHA03307; transcriptional regulator ICP4; Provisional
- cd00160
Location:772 → 958
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00992
Location:42 → 116
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13391
Location:976 → 1118
- PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
-
NM_001377419.1 → NP_001364348.1 rho guanine nucleotide exchange factor 11 isoform 4
Status: REVIEWED
- Source sequence(s)
-
AL157713, AL356104
- UniProtKB/TrEMBL
-
A0AAQ5BII7
- Conserved Domains (5) summary
-
- cd08753
Location:330 → 474
- RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
- PHA03307
Location:1202 → 1552
- PHA03307; transcriptional regulator ICP4; Provisional
- cd00160
Location:765 → 951
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00992
Location:46 → 120
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13391
Location:969 → 1111
- PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
-
NM_014784.4 → NP_055599.1 rho guanine nucleotide exchange factor 11 isoform 1
See identical proteins and their annotated locations for NP_055599.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the predominant isoform (1).
- Source sequence(s)
-
AB002378, AL157713, BC057394
- Consensus CDS
-
CCDS1162.1
- UniProtKB/Swiss-Prot
- D3DVD0, O15085, Q5VY40, Q6PFW2
- UniProtKB/TrEMBL
-
A0A2X0SFB0
- Related
- ENSP00000354644.2, ENST00000361409.2
- Conserved Domains (6) summary
-
- cd08753
Location:290 → 434
- RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
- COG0265
Location:61 → 139
- DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
- cd00992
Location:46 → 120
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13391
Location:939 → 1081
- PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
- pfam00169
Location:999 → 1079
- PH; PH domain
- pfam00621
Location:738 → 922
- RhoGEF; RhoGEF domain
-
NM_198236.3 → NP_937879.1 rho guanine nucleotide exchange factor 11 isoform 2
See identical proteins and their annotated locations for NP_937879.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) contains an alternate in-frame exon, compared to variant 1. The resulting protein (isoform 2) is longer, compared to isoform 1.
- Source sequence(s)
-
AL157713, BC057394
- Consensus CDS
-
CCDS1163.1
- UniProtKB/TrEMBL
-
A0AAQ5BII7
- Related
- ENSP00000357177.3, ENST00000368194.8
- Conserved Domains (6) summary
-
- cd08753
Location:330 → 474
- RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
- COG0265
Location:61 → 139
- DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
- cd00992
Location:46 → 120
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13391
Location:979 → 1121
- PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
- pfam00169
Location:1039 → 1119
- PH; PH domain
- pfam00621
Location:778 → 962
- RhoGEF; RhoGEF domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000001.11 Reference GRCh38.p14 Primary Assembly
- Range
-
156934840..157046903 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047435301.1 → XP_047291257.1 rho guanine nucleotide exchange factor 11 isoform X18
- UniProtKB/TrEMBL
-
A0A2X0SFB0
-
XM_047435294.1 → XP_047291250.1 rho guanine nucleotide exchange factor 11 isoform X14
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_047435306.1 → XP_047291262.1 rho guanine nucleotide exchange factor 11 isoform X19
- UniProtKB/TrEMBL
-
A0A2X0SFB0
-
XM_017002923.3 → XP_016858412.1 rho guanine nucleotide exchange factor 11 isoform X16
- UniProtKB/TrEMBL
-
A0A2X0SFB0
-
XM_047435300.1 → XP_047291256.1 rho guanine nucleotide exchange factor 11 isoform X17
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_047435285.1 → XP_047291241.1 rho guanine nucleotide exchange factor 11 isoform X12
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_047435284.1 → XP_047291240.1 rho guanine nucleotide exchange factor 11 isoform X11
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_005245629.6 → XP_005245686.1 rho guanine nucleotide exchange factor 11 isoform X8
- UniProtKB/TrEMBL
-
A0AAQ5BII7
- Conserved Domains (6) summary
-
- cd08753
Location:330 → 474
- RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
- COG0265
Location:61 → 139
- DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
- cd00992
Location:46 → 120
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13391
Location:980 → 1122
- PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
- pfam00169
Location:1040 → 1120
- PH; PH domain
- pfam00621
Location:779 → 963
- RhoGEF; RhoGEF domain
-
XM_017002920.3 → XP_016858409.1 rho guanine nucleotide exchange factor 11 isoform X6
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_017002924.3 → XP_016858413.1 rho guanine nucleotide exchange factor 11 isoform X15
- UniProtKB/TrEMBL
-
A0A2X0SFB0
-
XM_047435262.1 → XP_047291218.1 rho guanine nucleotide exchange factor 11 isoform X7
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_011510185.4 → XP_011508487.1 rho guanine nucleotide exchange factor 11 isoform X3
- UniProtKB/TrEMBL
-
A0AAQ5BII7
- Conserved Domains (6) summary
-
- cd08753
Location:341 → 485
- RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
- COG0265
Location:72 → 150
- DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
- cd00992
Location:57 → 131
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13391
Location:991 → 1133
- PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
- pfam00169
Location:1051 → 1131
- PH; PH domain
- pfam00621
Location:790 → 974
- RhoGEF; RhoGEF domain
-
XM_017002922.3 → XP_016858411.1 rho guanine nucleotide exchange factor 11 isoform X13
- UniProtKB/TrEMBL
-
A0A2X0SFB0
-
XM_006711665.5 → XP_006711728.1 rho guanine nucleotide exchange factor 11 isoform X10
- UniProtKB/TrEMBL
-
A0A2X0SFB0
- Conserved Domains (6) summary
-
- cd08753
Location:306 → 450
- RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
- COG0265
Location:77 → 155
- DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
- cd00992
Location:62 → 136
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13391
Location:955 → 1097
- PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
- pfam00169
Location:1015 → 1095
- PH; PH domain
- pfam00621
Location:754 → 938
- RhoGEF; RhoGEF domain
-
XM_011510186.4 → XP_011508488.1 rho guanine nucleotide exchange factor 11 isoform X9
- UniProtKB/TrEMBL
-
A0A2X0SFB0
- Conserved Domains (6) summary
-
- cd08753
Location:306 → 450
- RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
- COG0265
Location:77 → 155
- DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
- cd00992
Location:62 → 136
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13391
Location:956 → 1098
- PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
- pfam00169
Location:1016 → 1096
- PH; PH domain
- pfam00621
Location:755 → 939
- RhoGEF; RhoGEF domain
-
XM_006711662.4 → XP_006711725.1 rho guanine nucleotide exchange factor 11 isoform X5
- UniProtKB/TrEMBL
-
A0AAQ5BII7
- Conserved Domains (6) summary
-
- cd08753
Location:346 → 490
- RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
- COG0265
Location:77 → 155
- DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
- cd00992
Location:62 → 136
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13391
Location:985 → 1127
- PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
- pfam00169
Location:1045 → 1125
- PH; PH domain
- pfam00621
Location:784 → 968
- RhoGEF; RhoGEF domain
-
XM_006711660.5 → XP_006711723.1 rho guanine nucleotide exchange factor 11 isoform X2
- UniProtKB/TrEMBL
- A0AAQ5BII7, A0AAQ5BIK5
- Related
- ENSP00000520488.1, ENST00000715594.1
- Conserved Domains (6) summary
-
- cd08753
Location:346 → 490
- RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
- COG0265
Location:77 → 155
- DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
- cd00992
Location:62 → 136
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13391
Location:995 → 1137
- PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
- pfam00169
Location:1055 → 1135
- PH; PH domain
- pfam00621
Location:794 → 978
- RhoGEF; RhoGEF domain
-
XM_006711661.4 → XP_006711724.1 rho guanine nucleotide exchange factor 11 isoform X4
- UniProtKB/TrEMBL
-
A0AAQ5BII7
- Conserved Domains (6) summary
-
- cd08753
Location:346 → 490
- RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
- COG0265
Location:77 → 155
- DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
- cd00992
Location:62 → 136
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13391
Location:986 → 1128
- PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
- pfam00169
Location:1046 → 1126
- PH; PH domain
- pfam00621
Location:785 → 969
- RhoGEF; RhoGEF domain
-
XM_006711659.4 → XP_006711722.1 rho guanine nucleotide exchange factor 11 isoform X1
- UniProtKB/TrEMBL
-
A0AAQ5BII7
- Conserved Domains (6) summary
-
- cd08753
Location:346 → 490
- RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
- COG0265
Location:77 → 155
- DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
- cd00992
Location:62 → 136
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13391
Location:996 → 1138
- PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
- pfam00169
Location:1056 → 1136
- PH; PH domain
- pfam00621
Location:795 → 979
- RhoGEF; RhoGEF domain
-
XM_011510187.4 → XP_011508489.1 rho guanine nucleotide exchange factor 11 isoform X20
- UniProtKB/TrEMBL
-
A0AAQ5BII7
- Conserved Domains (5) summary
-
- cd08753
Location:252 → 396
- RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
- smart00228
Location:2 → 42
- PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
- cd13391
Location:902 → 1044
- PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
- pfam00169
Location:962 → 1042
- PH; PH domain
- pfam00621
Location:701 → 885
- RhoGEF; RhoGEF domain
-
XM_005245633.5 → XP_005245690.1 rho guanine nucleotide exchange factor 11 isoform X21
- UniProtKB/TrEMBL
-
B7Z7U2
- Conserved Domains (4) summary
-
- cd13391
Location:558 → 700
- PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
- pfam00169
Location:618 → 698
- PH; PH domain
- pfam00621
Location:357 → 541
- RhoGEF; RhoGEF domain
- cl02565
Location:2 → 105
- RGS; Regulator of G protein signaling (RGS) domain superfamily
-
XM_011510189.4 → XP_011508491.1 rho guanine nucleotide exchange factor 11 isoform X22
- UniProtKB/TrEMBL
-
B7Z7U2
- Conserved Domains (3) summary
-
- cd13391
Location:362 → 504
- PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
- pfam00169
Location:422 → 502
- PH; PH domain
- pfam00621
Location:161 → 345
- RhoGEF; RhoGEF domain
Alternate T2T-CHM13v2.0
Genomic
-
NC_060925.1 Alternate T2T-CHM13v2.0
- Range
-
156071681..156183721 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054339797.1 → XP_054195772.1 rho guanine nucleotide exchange factor 11 isoform X18
- UniProtKB/TrEMBL
-
A0A2X0SFB0
-
XM_054339793.1 → XP_054195768.1 rho guanine nucleotide exchange factor 11 isoform X14
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_054339798.1 → XP_054195773.1 rho guanine nucleotide exchange factor 11 isoform X19
- UniProtKB/TrEMBL
-
A0A2X0SFB0
-
XM_054339795.1 → XP_054195770.1 rho guanine nucleotide exchange factor 11 isoform X16
- UniProtKB/TrEMBL
-
A0A2X0SFB0
-
XM_054339796.1 → XP_054195771.1 rho guanine nucleotide exchange factor 11 isoform X17
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_054339791.1 → XP_054195766.1 rho guanine nucleotide exchange factor 11 isoform X12
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_054339790.1 → XP_054195765.1 rho guanine nucleotide exchange factor 11 isoform X11
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_054339787.1 → XP_054195762.1 rho guanine nucleotide exchange factor 11 isoform X8
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_054339785.1 → XP_054195760.1 rho guanine nucleotide exchange factor 11 isoform X6
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_054339794.1 → XP_054195769.1 rho guanine nucleotide exchange factor 11 isoform X15
- UniProtKB/TrEMBL
-
A0A2X0SFB0
-
XM_054339786.1 → XP_054195761.1 rho guanine nucleotide exchange factor 11 isoform X7
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_054339782.1 → XP_054195757.1 rho guanine nucleotide exchange factor 11 isoform X3
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_054339792.1 → XP_054195767.1 rho guanine nucleotide exchange factor 11 isoform X13
- UniProtKB/TrEMBL
-
A0A2X0SFB0
-
XM_054339789.1 → XP_054195764.1 rho guanine nucleotide exchange factor 11 isoform X10
- UniProtKB/TrEMBL
-
A0A2X0SFB0
-
XM_054339788.1 → XP_054195763.1 rho guanine nucleotide exchange factor 11 isoform X9
- UniProtKB/TrEMBL
-
A0A2X0SFB0
-
XM_054339784.1 → XP_054195759.1 rho guanine nucleotide exchange factor 11 isoform X5
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_054339781.1 → XP_054195756.1 rho guanine nucleotide exchange factor 11 isoform X2
- UniProtKB/TrEMBL
- A0AAQ5BII7, A0AAQ5BIK5
-
XM_054339783.1 → XP_054195758.1 rho guanine nucleotide exchange factor 11 isoform X4
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_054339780.1 → XP_054195755.1 rho guanine nucleotide exchange factor 11 isoform X1
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_054339799.1 → XP_054195774.1 rho guanine nucleotide exchange factor 11 isoform X20
- UniProtKB/TrEMBL
-
A0AAQ5BII7
-
XM_054339800.1 → XP_054195775.1 rho guanine nucleotide exchange factor 11 isoform X21
- UniProtKB/TrEMBL
-
B7Z7U2
-
XM_054339801.1 → XP_054195776.1 rho guanine nucleotide exchange factor 11 isoform X22
- UniProtKB/TrEMBL
-
B7Z7U2