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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029168.1 RefSeqGene
- Range
-
5168..18931
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001207012.1 → NP_001193941.1 placenta growth factor isoform 2 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region relative to variant 1. It encodes the shortest isoform (2, also known as PlGF-1 or PLGF-1), which lacks a 21 amino acid heparin binding domain found in variant 1 (PMID:8148155).
- Source sequence(s)
-
AC006530, BX248289, BX356823, X54936
- Consensus CDS
-
CCDS55932.1
- UniProtKB/Swiss-Prot
-
P49763
- UniProtKB/TrEMBL
-
Q86TW6
- Related
- ENSP00000451413.1, ENST00000553716.5
- Conserved Domains (2) summary
-
- PHA02661
Location:4 → 134
- PHA02661; vascular endothelial growth factor like protein; Provisional
- smart00141
Location:50 → 132
- PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
-
NM_001293643.1 → NP_001280572.1 placenta growth factor isoform 3 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) has an alternate splice site in the 5' coding region, compared to variant 1. The resulting isoform (3) lacks an internal aa, compared to isoform 1.
- Source sequence(s)
-
AC006530, AL543693, BX248289
- Consensus CDS
-
CCDS73664.1
- UniProtKB/TrEMBL
-
G3XA84
- Related
- ENSP00000238607.6, ENST00000238607.10
- Conserved Domains (2) summary
-
- PHA02661
Location:4 → 133
- PHA02661; vascular endothelial growth factor like protein; Provisional
- smart00141
Location:49 → 131
- PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
-
NM_002632.6 → NP_002623.2 placenta growth factor isoform 1 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes isoform 1 (also known as PlGF-2, PLGF-2 or PGF-2) and contains a 21 amino acid region that is thought to bind heparin (PMID:8148155).
- Source sequence(s)
-
AC006530
- Consensus CDS
-
CCDS9835.1
- UniProtKB/TrEMBL
-
Q53XY6
- Related
- ENSP00000451040.1, ENST00000555567.6
- Conserved Domains (2) summary
-
- PHA02661
Location:4 → 134
- PHA02661; vascular endothelial growth factor like protein; Provisional
- smart00141
Location:50 → 132
- PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000014.9 Reference GRCh38.p14 Primary Assembly
- Range
-
74941830..74955764 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047431476.1 → XP_047287432.1 placenta growth factor isoform X1
Alternate T2T-CHM13v2.0
Genomic
-
NC_060938.1 Alternate T2T-CHM13v2.0
- Range
-
69150944..69164879 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054376219.1 → XP_054232194.1 placenta growth factor isoform X1