Omd osteomodulin [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Omdprovided by RGD
Full Name: osteomodulinprovided by RGD
Primary source: RGD:621818
See related: EnsemblRapid:ENSRNOG00000039560 AllianceGenome:RGD:621818
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: OSAD
Summary: Predicted to be involved in cell adhesion. Predicted to be located in extracellular matrix. Predicted to be active in extracellular space. Orthologous to human OMD (osteomodulin). [provided by Alliance of Genome Resources, Dec 2024]
Annotation information: Note: The locus_ids 83717 and 103690116 are annotated independently on Rnor_6.0 (AR 105) assembly. [29 May 2015]
Expression: Biased expression in Heart (RPKM 62.1), Kidney (RPKM 56.7) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 17p14

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	17	NC_086035.1 (15266646..15274870, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	17	NC_051352.1 (15060217..15068441, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	17	NC_005116.4 (15476100..15484324, complement)

Chromosome 17 - NC_086035.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

may play an important role during tooth development and biomineralization of dentin
Title: Identification, distribution and expression of osteoadherin during tooth formation.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in cell adhesion	IEA Inferred from Electronic Annotation more info
involved_in regulation of bone mineralization	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular matrix	IEA Inferred from Electronic Annotation more info
located_in extracellular matrix	ISO Inferred from Sequence Orthology more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: osteomodulin

Names: KSPG osteomodulin; keratan sulfate proteoglycan osteomodulin; osteoadherin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_031817.2 → NP_114005.2 osteomodulin precursor

See identical proteins and their annotated locations for NP_114005.2

Status: VALIDATED

Source sequence(s)

JAXUCZ010000017

UniProtKB/Swiss-Prot

Q9Z1S7

UniProtKB/TrEMBL

A6J6V9, G3V7Y2

Related

ENSRNOP00000020648.2, ENSRNOT00000020648.6

Conserved Domains (4) summary

smart00013
Location:61 → 94

LRRNT; Leucine rich repeat N-terminal domain

cd00116
Location:136 → 342

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

sd00033
Location:94 → 116

LRR_RI; leucine-rich repeat [structural motif]

pfam13855
Location:96 → 153

LRR_8; Leucine rich repeat