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    Klf13 KLF transcription factor 13 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499171, updated on 9-Dec-2024

    Summary

    Official Symbol
    Klf13provided by RGD
    Official Full Name
    KLF transcription factor 13provided by RGD
    Primary source
    RGD:1565099
    See related
    EnsemblRapid:ENSRNOG00000015822 AllianceGenome:RGD:1565099
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565099
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of cell population proliferation and negative regulation of erythrocyte differentiation. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human KLF13 (KLF transcription factor 13). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 101.5), Spleen (RPKM 72.4) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Klf13 in Genome Data Viewer
    Location:
    1q22
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (126917671..126948436, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (117505857..117536626, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (124772596..124803363, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene OTU deubiquitinase 7A Neighboring gene ribosomal protein L7a, pseudogene 34 Neighboring gene uncharacterized LOC134483597 Neighboring gene small nucleolar RNA U3 Neighboring gene uncharacterized LOC102548601

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in nucleus  

    General protein information

    Preferred Names
    Krueppel-like factor 13
    Names
    Kruppel-like factor 13

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109147.1 → NP_001102617.1  Krueppel-like factor 13

      See identical proteins and their annotated locations for NP_001102617.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473980
      UniProtKB/TrEMBL
      A6JBK1, D3ZVI8
      Related
      ENSRNOP00000063436.1, ENSRNOT00000066380.3
      Conserved Domains (3) summary
      sd00017
      Location:42 → 64
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:70 → 92
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:56 → 79
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      126917671..126948436 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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