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    Tmem79 transmembrane protein 79 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310626, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmem79provided by RGD
    Official Full Name
    transmembrane protein 79provided by RGD
    Primary source
    RGD:1309886
    See related
    EnsemblRapid:ENSRNOG00000019414 AllianceGenome:RGD:1309886
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309886
    Summary
    Predicted to enable identical protein binding activity. Predicted to be involved in several processes, including epithelial cell maturation; establishment of skin barrier; and positive regulation of epidermis development. Predicted to act upstream of or within cornification; cuticle development; and hair follicle morphogenesis. Predicted to be located in cytoplasm. Predicted to be active in lysosomal membrane and trans-Golgi network membrane. Orthologous to human TMEM79 (transmembrane protein 79). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 73.2), Thymus (RPKM 37.8) and 6 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tmem79 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (176096092..176100996, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (173798267..173803151, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (187701522..187706452, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene ATP synthase subunit g, mitochondrial pseudogene Neighboring gene glycosylated lysosomal membrane protein Neighboring gene SMG5 nonsense mediated mRNA decay factor Neighboring gene progestin and adipoQ receptor family member 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC124716

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cornification ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cuticle development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in epithelial cell maturation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in epithelial cell maturation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within establishment of skin barrier ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment of skin barrier ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment of skin barrier ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within hair follicle morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of epidermis development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of epidermis development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulated exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulated exocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulated exocytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in lysosomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosomal membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in trans-Golgi network membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in trans-Golgi network membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in trans-Golgi network membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    transmembrane protein 79
    Names
    mattrin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033896.1NP_001029068.1  transmembrane protein 79

      See identical proteins and their annotated locations for NP_001029068.1

      Status: PROVISIONAL

      Source sequence(s)
      BC101913
      UniProtKB/Swiss-Prot
      Q3T1H8
      UniProtKB/TrEMBL
      A6J667
      Related
      ENSRNOP00000075750.1, ENSRNOT00000092349.3
      Conserved Domains (1) summary
      pfam01124
      Location:317355
      MAPEG; MAPEG family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      176096092..176100996 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006232637.5XP_006232699.1  transmembrane protein 79 isoform X1

      See identical proteins and their annotated locations for XP_006232699.1

      UniProtKB/Swiss-Prot
      Q3T1H8
      UniProtKB/TrEMBL
      A6J667
      Conserved Domains (1) summary
      pfam01124
      Location:317355
      MAPEG; MAPEG family
    2. XM_063281835.1XP_063137905.1  transmembrane protein 79 isoform X1

      UniProtKB/Swiss-Prot
      Q3T1H8
      UniProtKB/TrEMBL
      A6J667