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    Slc35a4 solute carrier family 35, member A4 [ Mus musculus (house mouse) ]

    Gene ID: 67843, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Slc35a4provided by MGI
    Official Full Name
    solute carrier family 35, member A4provided by MGI
    Primary source
    MGI:MGI:1915093
    See related
    Ensembl:ENSMUSG00000033272 AllianceGenome:MGI:1915093
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2610030J16Rik
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in positive regulation of translation in response to stress and transmembrane transport. Predicted to be located in Golgi apparatus. Predicted to be active in Golgi membrane. Is expressed in axial musculature; cranium; olfactory cortex ventricular layer; and telencephalon ventricular layer. Orthologous to human SLC35A4 (solute carrier family 35 member A4). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 89.9), adrenal adult (RPKM 87.5) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Slc35a4 in Genome Data Viewer
    Location:
    18 B2; 18 19.46 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (36812268..36816915)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (36679215..36683862)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 4E binding protein 3 Neighboring gene STARR-positive B cell enhancer ABC_E5653 Neighboring gene steroid receptor RNA activator 1 Neighboring gene amyloid beta precursor protein binding family B member 3 Neighboring gene STARR-positive B cell enhancer ABC_E8708 Neighboring gene Riken cDNA E230025N22 gene Neighboring gene STARR-seq mESC enhancer starr_44297 Neighboring gene predicted gene, 41699

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579
    2. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
    3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC143687, MGC143688

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of translation in response to stress ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    probable UDP-sugar transporter protein SLC35A4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083317.2 → NP_001076786.1  probable UDP-sugar transporter protein SLC35A4

      See identical proteins and their annotated locations for NP_001076786.1

      Status: VALIDATED

      Source sequence(s)
      AC115631
      Consensus CDS
      CCDS29158.1
      UniProtKB/Swiss-Prot
      Q8BMH3, Q99JK8, Q9D0A7, Q9D321
      Related
      ENSMUSP00000129718.2, ENSMUST00000050476.11
      Conserved Domains (1) summary
      pfam04142
      Location:83 → 320
      Nuc_sug_transp; Nucleotide-sugar transporter

    2. NM_001360989.2 → NP_001347918.1  probable UDP-sugar transporter protein SLC35A4

      Status: VALIDATED

      Source sequence(s)
      AC115631
      Consensus CDS
      CCDS29158.1
      UniProtKB/Swiss-Prot
      Q8BMH3, Q99JK8, Q9D0A7, Q9D321
      Conserved Domains (1) summary
      pfam04142
      Location:83 → 320
      Nuc_sug_transp; Nucleotide-sugar transporter

    3. NM_026404.3 → NP_080680.2  probable UDP-sugar transporter protein SLC35A4

      See identical proteins and their annotated locations for NP_080680.2

      Status: VALIDATED

      Source sequence(s)
      AC115631
      Consensus CDS
      CCDS29158.1
      UniProtKB/Swiss-Prot
      Q8BMH3, Q99JK8, Q9D0A7, Q9D321
      Related
      ENSMUSP00000036081.7, ENSMUST00000036158.7
      Conserved Domains (1) summary
      pfam04142
      Location:83 → 320
      Nuc_sug_transp; Nucleotide-sugar transporter

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      36812268..36816915
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D321.1 GenPept UniProtKB/Swiss-Prot:Q9D321

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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