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    Igh-VS107 immunoglobulin heavy chain (S107 family) [ Mus musculus (house mouse) ]

    Gene ID: 16065, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Igh-VS107provided by MGI
    Official Full Name
    immunoglobulin heavy chain (S107 family)provided by MGI
    Primary source
    MGI:MGI:96490
    Gene type
    other
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    IgG; IgH; VhNZA6
    Annotation information
    not in current annotation release
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    Genomic context

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    Location:
    12 F1; 12

    Bibliography

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    Related articles in PubMed

    1. The organization, expression, and evolution of antibody genes and other multigene families. Hood L, et al. Annu Rev Genet, 1975. PMID 813561
    2. Interaction and sequence diversity among T15 VH genes in CBA/J mice. Ferguson SE, et al. J Exp Med, 1988 Oct 1. PMID 3139820, Free PMC Article
    3. Polyreactive IgM antibodies generated from autoimmune mice and selected for histone-binding activity. Novick KE, et al. Int Immunol, 1992 Oct. PMID 1489729
    4. Somatic diversification of the S107 (T15) VH11 germ-line gene that encodes the heavy-chain variable region of antibodies to double-stranded DNA in (NZB x NZW)F1 mice. Behar SM, et al. Proc Natl Acad Sci U S A, 1988 Jun. PMID 3131767, Free PMC Article
    5. Somatic diversification of S107 from an antiphosphocholine to an anti-DNA autoantibody is due to a single base change in its heavy chain variable region. Giusti AM, et al. Proc Natl Acad Sci U S A, 1987 May. PMID 3106981, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A natural IgG binds to fibrinogen deposited in elastase-perfused aortic tissues and activates the complement lectin pathway, inducing an abdominal aortic aneurysm.
      Title: Fibrinogen-specific antibody induces abdominal aortic aneurysm in mice through complement lectin pathway activation.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • IgMk heavy chain variable region
    • VH coding region
    • anti-poly(dC) monoclonal antibody heavy chain
    • immunoglobulin variable region
    Nucleotide Protein Strain
    Heading Accession and Version

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