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    Cyp6a21 Cytochrome P450 6a21 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36665, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cyp6a21provided by FlyBase
    Official Full Name
    Cytochrome P450 6a21provided by FlyBase
    Primary source
    FLYBASE:FBgn0288232
    Locus tag
    Dmel_CG10247
    See related
    AllianceGenome:FB:FBgn0288232
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    6a21; AF4-2; CG10247; cyp6a21; Cyp6A21; CYP6A21; Cyp6a9-rAF4-2; Dmel\CG10247; P-450; P450
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Is expressed in adult fat body; adult head; embryonic/larval midgut; organism; and yolk. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cyp6a21 in Genome Data Viewer
    Location:
    51D1-51D1; 2-73 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14885264..14886947, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10772769..10774452, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Cytochrome P450 6a19 Neighboring gene Cytochrome P450 6a9 Neighboring gene Cytochrome P450 6a20 Neighboring gene Cytochrome P450 6a8 Neighboring gene Cytochrome P450 317a1 Neighboring gene kank

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Three second chromosome-linked clustered Cyp6 genes show differential constitutive and barbital-induced expression in DDT-resistant and susceptible strains of Drosophila melanogaster. Maitra S, et al. Gene, 1996 Nov 21. PMID 8973362
    2. Neural clocks and Neuropeptide F/Y regulate circadian gene expression in a peripheral metabolic tissue. Erion R, et al. Elife, 2016 Apr 14. PMID 27077948, Free PMC Article
    3. Feminization of pheromone-sensing neurons affects mating decisions in Drosophila males. Lu B, et al. Biol Open, 2014 Feb 15. PMID 24463366, Free PMC Article
    4. Alkaloid metabolism by cytochrome P-450 enzymes in Drosophila melanogaster. Danielson PB, et al. Comp Biochem Physiol B Biochem Mol Biol, 1995 Apr. PMID 7749620
    5. [Ethanol inhibits recombination in somatic cells of gamma-irradiated larvae of Drosophila melanogaster]. Zakharenko LP, et al. Genetika, 1998 Mar. PMID 9589864

    See all (53) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450 6a21
    Names
    CG10247-PA
    Cyp6a21-PA
    Cyp6a9-related
    cytochrome P450
    cytochrome P450-6a9 related AF4-2
    NP_611003.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      14885264..14886947 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137159.4 → NP_611003.2  cytochrome P450 6a21 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611003.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8E6J3, Q8SZL2, Q9V774
      Related
      FBpp0086586
      Conserved Domains (1) summary
      pfam00067
      Location:35 → 499
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V774.1 Q9V774

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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