U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Ref2 RNA and export factor binding protein 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34667, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Ref2provided by FlyBase
    Official Full Name
    RNA and export factor binding protein 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0032439
    Locus tag
    Dmel_CG17031
    See related
    AllianceGenome:FB:FBgn0032439
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg17031; CG17031; Dmel\CG17031; ref2; REF2
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Ref2 in Genome Data Viewer
    Location:
    33F1-33F2; 2-47 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (12610517..12646356, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (12610517..12646356, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44597 Neighboring gene long non-coding RNA:CR44596 Neighboring gene long non-coding RNA:CR44595 Neighboring gene nubbin Neighboring gene POU domain protein 2 Neighboring gene Neprilysin-like 7 Neighboring gene Chaperonin containing TCP1 subunit 4

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Dendritic diversification through transcription factor-mediated suppression of alternative morphologies. Corty MM, et al. Development, 2016 Apr 15. PMID 27095495, Free PMC Article
    2. REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export. Gatfield D, et al. J Cell Biol, 2002 Nov 25. PMID 12438415, Free PMC Article
    3. New genes in Drosophila quickly become essential. Chen S, et al. Science, 2010 Dec 17. PMID 21164016, Free PMC Article
    4. Chromatin state transitions in the Drosophila intestinal lineage identify principles of cell-type specification. Josserand M, et al. Dev Cell, 2023 Dec 18. PMID 38056452
    5. New genes often acquire male-specific functions but rarely become essential in Drosophila. Kondo S, et al. Genes Dev, 2017 Sep 15. PMID 29051389, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    RNA and export factor binding protein 2
    Names
    CG17031-PA
    CG17031-PB
    CG17031-PC
    Ref2-PA
    Ref2-PB
    Ref2-PC
    ref2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      12610517..12646356 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001259078.2 → NP_001246007.1  RNA and export factor binding protein 2, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246007.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0IGZ5, Q9VK76
      Conserved Domains (2) summary
      COG0724
      Location:2 → 198
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cl17169
      Location:75 → 149
      RRM_SF; RNA recognition motif (RRM) superfamily

    2. NM_001259079.2 → NP_001246008.1  RNA and export factor binding protein 2, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246008.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0IGZ5, Q9VK76
      Conserved Domains (2) summary
      COG0724
      Location:2 → 198
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cl17169
      Location:75 → 149
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. NM_135730.3 → NP_609574.1  RNA and export factor binding protein 2, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609574.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0IGZ5, Q9VK76
      Related
      FBpp0079958
      Conserved Domains (2) summary
      COG0724
      Location:2 → 198
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cl17169
      Location:75 → 149
      RRM_SF; RNA recognition motif (RRM) superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IFW5 Q8IFW5
    Q9VK76 Q9VK76

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools