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    SNHG7 small nucleolar RNA host gene 7 [ Homo sapiens (human) ]

    Gene ID: 84973, updated on 10-Dec-2024

    Summary

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    Official Symbol
    SNHG7provided by HGNC
    Official Full Name
    small nucleolar RNA host gene 7provided by HGNC
    Primary source
    HGNC:HGNC:28254
    See related
    Ensembl:ENSG00000233016 AllianceGenome:HGNC:28254
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NCRNA00061
    Summary
    Predicted to be involved in RNA processing. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in ovary (RPKM 15.1), thyroid (RPKM 12.1) and 25 other tissues See more
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    Genomic context

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    See SNHG7 in Genome Data Viewer
    Location:
    9q34.3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (136724594..136728184, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (148957775..148961362, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (139619046..139622636, complement)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene EGF like domain multiple 7 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139569227-139569726 Neighboring gene microRNA 126 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139573281-139573980 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139573981-139574680 Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:139576202-139577064 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:139580514-139581375 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20536 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20537 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:139591540-139592050 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:139592051-139592559 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29319 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29320 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:139607687-139608611 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29321 Neighboring gene cuticle collagen 2-like Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29322 Neighboring gene divergent protein kinase domain 1B Neighboring gene Sharpr-MPRA regulatory region 5701 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20538 Neighboring gene ReSE screen-validated silencer GRCh37_chr9:139623217-139623386 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29323 Neighboring gene small nucleolar RNA, H/ACA box 17B Neighboring gene small nucleolar RNA, H/ACA box 17A Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139627044-139627888 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139629713-139630212 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20539 Neighboring gene uncharacterized LOC100128593 Neighboring gene lipocalin 10 Neighboring gene microRNA 6722 Neighboring gene lipocalin 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Abnormal Expression of SNHG7 Is a Biomarker for the Diagnosis and Prognosis of Neonatal Sepsis. Li L, et al. Tohoku J Exp Med, 2022 Nov 11. PMID 35965096
    2. LncRNA SNHG7 contributes to cell proliferation, invasion and prognosis of cervical cancer. Zeng J, et al. Eur Rev Med Pharmacol Sci, 2019 Nov. PMID 31773679
    3. Long noncoding RNA SNHG7 contributes to cell proliferation, migration, invasion and epithelial to mesenchymal transition in non-small cell lung cancer by regulating miR-449a/TGIF2 axis. Pang L, et al. Thorac Cancer, 2020 Feb. PMID 31793741, Free PMC Article
    4. LncRNA SNHG7 promotes development of breast cancer by regulating microRNA-186. Luo X, et al. Eur Rev Med Pharmacol Sci, 2018 Nov. PMID 30536320
    5. Long non-coding RNA small nucleolar RNA host gene 7 expression level in prostate cancer tissues predicts the prognosis of patients with prostate cancer. Xia Q, et al. Medicine (Baltimore), 2020 Feb. PMID 32049793, Free PMC Article

    See all (52) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Abnormal Expression of SNHG7 Is a Biomarker for the Diagnosis and Prognosis of Neonatal Sepsis.
      Title: Abnormal Expression of SNHG7 Is a Biomarker for the Diagnosis and Prognosis of Neonatal Sepsis.
    2. Metformin Affects Paclitaxel Sensitivity of Ovarian Cancer Cells Through Autophagy Mediated by Long Noncoding RNASNHG7/miR-3127-5p Axis.
      Title: Metformin Affects Paclitaxel Sensitivity of Ovarian Cancer Cells Through Autophagy Mediated by Long Noncoding RNASNHG7/miR-3127-5p Axis.
    3. The Prognostic Value of Long Non-Coding RNA SNHG7 in Human Cancer: A Meta-Analysis.
      Title: The Prognostic Value of Long Non-Coding RNA SNHG7 in Human Cancer: A Meta-Analysis.
    4. METTL3-stabilized lncRNA SNHG7 accelerates glycolysis in prostate cancer via SRSF1/c-Myc axis.
      Title: METTL3-stabilized lncRNA SNHG7 accelerates glycolysis in prostate cancer via SRSF1/c-Myc axis.
    5. LncRNA SNHG7 Promotes the HCC Progression Through miR-122-5p/FOXK2 Axis.
      Title: LncRNA SNHG7 Promotes the HCC Progression Through miR-122-5p/FOXK2 Axis.
    6. Long non-coding RNA (LncRNA) SNHG7/ Eukaryotic translation initiation factor 4 gamma 2 (EIF4G2) involves in the malignant events of ovarian cancer cells with paclitaxel resistant.
      Title: Long non-coding RNA (LncRNA) SNHG7/ Eukaryotic translation initiation factor 4 gamma 2 (EIF4G2) involves in the malignant events of ovarian cancer cells with paclitaxel resistant.
    7. Downregulation of long noncoding RNA SNHG7 protects against inflammation and apoptosis in Parkinson's disease model by targeting the miR-425-5p/TRAF5/NF-kappaB axis.
      Title: Downregulation of long noncoding RNA SNHG7 protects against inflammation and apoptosis in Parkinson's disease model by targeting the miR-425-5p/TRAF5/NF-κB axis.
    8. Exosome-mediated transfer of SNHG7 enhances docetaxel resistance in lung adenocarcinoma.
      Title: Exosome-mediated transfer of SNHG7 enhances docetaxel resistance in lung adenocarcinoma.
    9. MicroRNA-21 inhibits ovarian granulosa cell proliferation by targeting SNHG7 in premature ovarian failure with polycystic ovary syndrome.
      Title: MicroRNA-21 inhibits ovarian granulosa cell proliferation by targeting SNHG7 in premature ovarian failure with polycystic ovary syndrome.
    10. Clinicopathological and prognostic value of long noncoding RNA SNHG7 in cancers: a meta-analysis and bioinformatics.
      Title: Clinicopathological and prognostic value of long noncoding RNA SNHG7 in cancers: a meta-analysis and bioinformatics.
    Submit: New GeneRIF Correction See all GeneRIFs (48)

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • small nucleolar RNA host gene (non-protein coding) 7
    • small nucleolar RNA host gene 7 (non-protein coding)

    Clone Names

    • MGC16037

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_003672.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) has an unspliced 3' sequence and is the longest transcript.
      Source sequence(s)
      AL355987
      Related
      ENST00000447221.1

    2. NR_024542.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) consists of four exons and the 3' sequence is spliced, as compared to variant 1.
      Source sequence(s)
      BC042369, BC059956, BC061888
      Related
      ENST00000761662.1

    3. NR_024543.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) consists of five exons and the 3' sequence is spliced, as compared to variant 1.
      Source sequence(s)
      BC042369, BC059956, BC061888

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      136724594..136728184 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060933.1 Alternate T2T-CHM13v2.0

      Range
      148957775..148961362 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_032887.1: Suppressed sequence

      Description
      NM_032887.1: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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    Research Materials