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    CG6432 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42901, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6432provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039184
    Locus tag
    Dmel_CG6432
    See related
    AllianceGenome:FB:FBgn0039184
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6432
    Summary
    Predicted to enable propionate-CoA ligase activity. Predicted to be involved in fatty acid biosynthetic process. Predicted to be active in mitochondrial matrix. Is expressed in adult fat body and adult head. Orthologous to human ACSS3 (acyl-CoA synthetase short chain family member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6432 in Genome Data Viewer
    Location:
    95F14-95F14; 3-84 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24336922..24340645)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20162644..20166367)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR46093 Neighboring gene BRWD3 Neighboring gene Ribosomal RNA Processing 5 Neighboring gene Dis3 Neighboring gene mir-1015 stem loop Neighboring gene Myosuppressin Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Membrane lipid physiology and toxin catabolism underlie ethanol and acetic acid tolerance in Drosophila melanogaster. Montooth KL, et al. J Exp Biol, 2006 Oct. PMID 16985200
    2. The Splicing Factor RNA-Binding Fox Protein 1 Mediates the Cellular Immune Response in Drosophila melanogaster. Nazario-Toole AE, et al. J Immunol, 2018 Aug 15. PMID 29997126, Free PMC Article
    3. A fatty acid anabolic pathway in specialized-cells sustains a remote signal that controls egg activation in Drosophila. Poidevin M, et al. PLoS Genet, 2024 Mar. PMID 38483976, Free PMC Article
    4. Nuclear translocation ability of Lipin differentially affects gene expression and survival in fed and fasting Drosophila. Hood SE, et al. J Lipid Res, 2020 Dec. PMID 32989002, Free PMC Article
    5. RNA degradation is required for the germ-cell to maternal transition in Drosophila. Blatt P, et al. Curr Biol, 2021 Jul 26. PMID 33989522, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables propionate-CoA ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6432-PA
    CG6432-PB
    NP_001287502.1
    NP_651247.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      24336922..24340645
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300573.1 → NP_001287502.1  uncharacterized protein Dmel_CG6432, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287502.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VC92
      Conserved Domains (2) summary
      PRK10524
      Location:28 → 657
      prpE; propionyl-CoA synthetase; Provisional
      cd05967
      Location:37 → 651
      PrpE; Propionyl-CoA synthetase (PrpE)

    2. NM_142990.2 → NP_651247.1  uncharacterized protein Dmel_CG6432, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651247.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VC92
      Related
      FBpp0083990, FBtr0084606
      Conserved Domains (2) summary
      PRK10524
      Location:28 → 657
      prpE; propionyl-CoA synthetase; Provisional
      cd05967
      Location:37 → 651
      PrpE; Propionyl-CoA synthetase (PrpE)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VC92 Q9VC92

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