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    SUR7 Sur7p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854953, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SUR7
    Official Full Name
    Sur7p
    Primary source
    SGD:S000004516
    Locus tag
    YML052W
    See related
    AllianceGenome:SGD:S000004516; FungiDB:YML052W; VEuPathDB:YML052W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in ascospore formation; endocytosis; and protein localization to eisosome filament. Located in cell cortex; eisosome; and plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SUR7 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (170402..171310)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene tRNA-Tyr Neighboring gene uncharacterized protein Neighboring gene transcription regulator GAL80 Neighboring gene Aim32p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Antisense expression increases gene expression variability and locus interdependency. Xu Z, et al. Mol Syst Biol, 2011 Feb 15. PMID 21326235, Free PMC Article
    2. Evolutionarily conserved 5'-3' exoribonuclease Xrn1 accumulates at plasma membrane-associated eisosomes in post-diauxic yeast. Grousl T, et al. PLoS One, 2015. PMID 25811606, Free PMC Article
    3. The Sur7p family defines novel cortical domains in Saccharomyces cerevisiae, affects sphingolipid metabolism, and is involved in sporulation. Young ME, et al. Mol Cell Biol, 2002 Feb. PMID 11784867, Free PMC Article
    4. Distribution of Can1p into stable domains reflects lateral protein segregation within the plasma membrane of living S. cerevisiae cells. Malinska K, et al. J Cell Sci, 2004 Dec 1. PMID 15536122
    5. Periprotein lipidomes of Saccharomyces cerevisiae provide a flexible environment for conformational changes of membrane proteins. van 't Klooster JS, et al. Elife, 2020 Apr 17. PMID 32301705, Free PMC Article

    See all (56) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in ascospore formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cortical actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in fungal-type cell wall organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein localization to eisosome filament IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in septin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell cortex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cell cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell periphery HDA PubMed 
    located_in eisosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in membrane raft IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion HDA PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Sur7p
    NP_013660.1
    • Plasma membrane protein, component of eisosomes; long-lived protein that remains stable in eisosomes of mother cells while other eisosome proteins, Pil1p and Lsp1p, turn over; may function to anchor the eisosome in place; sporulation and plasma membrane sphingolipid content are altered in mutants; localizes to furrow-like invaginations (MCC patches)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      170402..171310
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182410.1 → NP_013660.1  TPA: Sur7p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013660.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZC3, P54003
      UniProtKB/TrEMBL
      A6ZM15, B3LLK5, C7GS68, C8ZEF6, G2WK05, N1NZ06
      Conserved Domains (1) summary
      pfam06687
      Location:18 → 206
      SUR7; SUR7/PalI family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P54003.1

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