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    HXT9 hexose transporter HXT9 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853236, updated on 9-Dec-2024

    Summary

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    Official Symbol
    HXT9
    Official Full Name
    hexose transporter HXT9
    Primary source
    SGD:S000003755
    Locus tag
    YJL219W
    See related
    AllianceGenome:SGD:S000003755; FungiDB:YJL219W; VEuPathDB:YJL219W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables hexose transmembrane transporter activity. Involved in hexose transmembrane transport. Located in cell periphery and fungal-type vacuole. Orthologous to human SLC2A6 (solute carrier family 2 member 6) and SLC2A8 (solute carrier family 2 member 8). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See HXT9 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (19497..21200)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene signal sequence-binding protein Neighboring gene oligo-1,6-glucosidase IMA4 Neighboring gene acetyltransferase Neighboring gene Ree1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Improving L-arabinose utilization of pentose fermenting Saccharomyces cerevisiae cells by heterologous expression of L-arabinose transporting sugar transporters. Subtil T, et al. Biotechnol Biofuels, 2011 Oct 12. PMID 21992610, Free PMC Article
    2. Sequence analysis of a 40.2 kb DNA fragment located near the left telomere of yeast chromosome X. Vandenbol M, et al. Yeast, 1994 Dec. PMID 7725802
    3. Mammalian glucose permease GLUT1 facilitates transport of arsenic trioxide and methylarsonous acid. Liu Z, et al. Biochem Biophys Res Commun, 2006 Dec 15. PMID 17064664, Free PMC Article
    4. Multiple-drug-resistance phenomenon in the yeast Saccharomyces cerevisiae: involvement of two hexose transporters. Nourani A, et al. Mol Cell Biol, 1997 Sep. PMID 9271421, Free PMC Article
    5. Arsenic trioxide uptake by hexose permeases in Saccharomyces cerevisiae. Liu Z, et al. J Biol Chem, 2004 Apr 23. PMID 14966117

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables D-glucose transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables carbohydrate:proton symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables fructose transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables galactose transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables mannose transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fructose transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in galactose transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in hexose transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mannose transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in fungal-type vacuole HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    hexose transporter HXT9
    NP_012316.1
    • Putative hexose transporter that is nearly identical to Hxt11p; has similarity to major facilitator superfamily (MFS) transporters, expression of HXT9 is regulated by transcription factors Pdr1p and Pdr3p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      19497..21200
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181652.1 → NP_012316.1  TPA: hexose transporter HXT9 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012316.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVX7, P40885
      UniProtKB/TrEMBL
      C8ZB02
      Conserved Domains (1) summary
      pfam00083
      Location:64 → 526
      Sugar_tr; Sugar (and other) transporter
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40885.1

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