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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001160415.1 → NP_001153887.1 DNA dC->dU-editing enzyme APOBEC-3 isoform 1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longer isoform (1).
- Source sequence(s)
-
AC113595
- Consensus CDS
-
CCDS49669.1
- UniProtKB/Swiss-Prot
- H3BJL0, Q8C7L0, Q8C8V7, Q99J72
- UniProtKB/TrEMBL
-
E9QMH1
- Related
- ENSMUSP00000105249.4, ENSMUST00000109620.10
- Conserved Domains (3) summary
-
- cd01283
Location:35 → 141
- cytidine_deaminase; Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on ...
- pfam05240
Location:137 → 182
- APOBEC_C; APOBEC-like C-terminal domain
- pfam08210
Location:26 → 195
- APOBEC_N; APOBEC-like N-terminal domain
-
NM_001347041.1 → NP_001333970.1 DNA dC->dU-editing enzyme APOBEC-3 isoform 3
Status: VALIDATED
- Source sequence(s)
-
AC113595
- Consensus CDS
-
CCDS84179.1
- UniProtKB/TrEMBL
-
Q3TI69
- Related
- ENSMUSP00000023054.8, ENSMUST00000023054.14
- Conserved Domains (2) summary
-
- pfam18772
Location:1 → 99
- APOBEC2
- pfam18782
Location:102 → 264
- NAD2; Novel AID APOBEC clade 2
-
NM_030255.3 → NP_084531.2 DNA dC->dU-editing enzyme APOBEC-3 isoform 2
See identical proteins and their annotated locations for NP_084531.2
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) lacks an alternate in-frame exon in the coding region, compared to variant 1. The encoded isoform (2)is shorter than isoform 1.
- Source sequence(s)
-
AA288216, AK049256, AK153719, BY228556
- Consensus CDS
-
CCDS27654.1
- UniProtKB/TrEMBL
- B5T0I9, Q3U5C5
- Related
- ENSMUSP00000132391.2, ENSMUST00000165537.8
- Conserved Domains (3) summary
-
- cd01283
Location:35 → 141
- cytidine_deaminase; Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on ...
- pfam05240
Location:137 → 182
- APOBEC_C; APOBEC-like C-terminal domain
- pfam08210
Location:26 → 195
- APOBEC_N; APOBEC-like N-terminal domain